摘要
目的探讨头孢菌素与阿奇霉素联用序贯治疗小儿支气管肺炎的临床疗效.方法选取无锡虹桥医院2017年8月至2019年8月收治的102例支气管肺炎患儿,采用随机数字表法分为观察组和对照组,各51例.观察组患儿采取头孢菌素联合阿奇霉素序贯疗法进行治疗,对照组患者采取头孢菌素联合阿奇霉素进行治疗.比较两组临床疗效及不良反应发生率.结果观察组患儿的治疗总有效率显著高于对照组,差异有统计学意义(94.12%vs.80.39%,P<0.05).观察组患儿的恶心呕吐、腹痛腹胀、关节疼痛、食欲不振等不良反应发生率显著低于对照组,差异有统计学意义(15.69%vs.31.37%,P<0.05).结论头孢菌素联合阿奇霉素序贯治疗小儿支气管肺炎,能够显著提高患儿的临床治疗效果,同时能够降低药物不良反应发生率.
Objective To investigate the clinical effect of sequential therapy of cephalosporin combined with azithromycin in the treatment of bronchopneumonia in children.Methods A total of 102 children with bronchopneumonia received in Wuxi Hongqiao Hospital from August 2017 to August 2019 were randomly divided into an observation group and a control group,51 cases per group.The children in the observation group were treated with sequential therapy of cephalosporin combined with azithromycin,while the patients in the control group were treated with cephalosporin combined with azithromycin.The clinical effect and incidence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group was significantly higher than that of the control group(94.12%vs.80.39%P<0.05).The incidence of nausea and vomiting,abdominal pain,abdominal distension,joint pain and anorexia in the observation group was significantly lower than that in the control group(15.69%vs.31.37%,P<0.05).Conclusion The sequential therapy of cephalosporin combined with azithromycin on bronchopneumonia in children can significantly improve the clinical effect,and reduce the incidence of adverse drug reactions.
作者
周云
李宗峰
梅斌
ZHOU Yun;LI Zongfeng;MEI Bin(Wuxi Hongqiao Hospital,Wuxi,Jiangsu 214000,China)
出处
《大医生》
2019年第20期125-126,共2页
Doctor
关键词
头孢菌素
阿奇霉素
序贯治疗
小儿支气管肺炎
cephalosporin
azithromycin
sequential therapy
bronchopneumonia in children
