摘要
目的:优选伤科凝胶剂处方的最佳提取工艺。方法:选取溶媒浓度、溶媒量、提取次数、提取时间为考察因素,以士的宁提取量和浸膏收率为指标,采用正交试验设计法优选伤科凝胶剂处方的最佳提取工艺。结果:确定伤科凝胶剂处方最佳提取工艺为10、8、8倍60%乙醇加热回流提取3次,每次1.5 h,合并提取液。结论:该提取工艺稳定可靠,科学合理,适合于伤科凝胶剂的工业化提取,可作为伤科凝胶剂处方质量的评价方法。
Objective:To determine the best of Shangke gels preparation process.Methods:The added alcohol quantity,extracting time,extraction times were selected as investigating factors,strychnine concentration and extract yield were used for total extraction quantity index,Orthogonal experimental design method was applied to optimized the extraction technology standard prescription.Results:The best extraction technology of Shangke gels was determined that 10,8,8 times,by 60%ethanol reflux extraction 3 times,each time 1.5 hours.Conclusion:The extraction process is rational and scientific,and stable and reliable,and suitable for the industrialization of the agent gels extraction.And it can be as Shangke gels prescription quality evaluation method.
作者
侯影
张旭
HOU Ying;ZHANG Xu(The First Affiliated Hospital of Liaoning University of TCM,Shenyang 110032,China;Liaoning University of Traditional Chinese Medicine,Dalian 116600,China)
出处
《中国现代中药》
CAS
2020年第1期89-93,共5页
Modern Chinese Medicine
关键词
伤科凝胶剂
士的宁
提取工艺
Shangke gels
strychnine
extraction process
