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唑来膦酸联合89Sr治疗前列腺癌骨转移的临床疗效 被引量:6

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摘要 目的探讨前列腺癌骨转移治疗中唑来膦酸联合氯化锶(89Sr)的应用效果。方法 86例前列腺癌骨转移患者为研究对象,根据随机数字表法将其分为对照组及观察组,各43例。对照组采用单一89Sr治疗,观察组在对照组基础上联合运用唑来膦酸治疗。比较两组患者的骨痛缓解起效时间,骨痛疗效,骨转移灶疗效,不良反应发生情况。结果观察组的骨痛缓解起效时间为(5.23±1.08)d,明显短于对照组的(7.10±1.34)d,差异具有统计学意义(P<0.05)。观察组的骨痛缓解率为88.37%,高于对照组的67.44%,差异具有统计学意义(P<0.05)。观察组的骨转移灶治疗有效率为51.16%,高于对照组的30.23%,差异具有统计学意义(P<0.05)。观察组的不良反应发生率略低于对照组,但差异均无统计学意义(P>0.05)。结论临床上给予前列腺癌骨转移患者唑来膦酸联合89Sr治疗的效果显著。
作者 赵斌
出处 《中国实用医药》 2020年第4期114-116,共3页 China Practical Medicine
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