摘要
尿毒症心肌病是慢性肾脏病(CKD)患者死亡的主要原因之一,其产生与血流动力学异常、尿毒症毒素等多种因素综合作用密切相关。左心室肥厚(LVH)是CKD患者最常见的心脏改变,一般是预后不良的信号,是CKD患者发生心律失常、心肌缺血、心力衰竭,甚至猝死的独立危险因素。目前尿毒症心肌病的发生机制尚未阐明,治疗方法还需进一步研究,文章对尿毒症心肌病的诊断与治疗研究进展进行综述。
Uremic cardiomyopathy is one of the main causes of death in patients with chronic kidney disease(CKD),which is closely related to hemodynamic abnormalities,uremic toxins and other factors.Left ventricular hypertrophy(LVH)is the most common cardiac change in CKD patients,which is generally a signal of poor prognosis.It is an independent risk factor for arrhythmia,myocardial ischemia,heart failure and even sudden death in CKD patients.At present,the pathogenesis of uremic cardiomyopathy has not been clarified,and the treatment method needs further study.This paper reviews the research progress of diagnosis and treatment of uremic cardiomyopathy.
作者
蒲玲
丁国华
Pu Ling;Ding Guohua(Department of Nephrology,Renmin Hospital,Wuhan University,Hubei Province,Wuhan 430060,China)
出处
《疑难病杂志》
CAS
2020年第3期302-306,共5页
Chinese Journal of Difficult and Complicated Cases
基金
国家自然科学基金资助项目(81770687)~~
关键词
尿毒症
心肌病
诊断
治疗
Uremia
Cardiomyopathy
Diagnosis
Treatment
