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联合运用通窍活血汤与丁苯酞胶囊治疗卒中后血管性认知障碍的可行性研究 被引量:5

Feasibility Study of Combined Use of Tongqiao Huoxue Decoction and Butylphthalide Capsule in the Treatment of Post-stroke Vascular Cognitive Impairment
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摘要 目的:对治疗卒中后血管性认知障碍的患者中联合运用通窍活血汤与丁苯酞胶囊的临床效果展开研究。方法:选取笔者所在医院2018年3月-2019年5月神经内科收治的卒中后血管性认知障碍的患者80例展开研究,随机分为两组。在常规治疗基础上,对照组40例丁苯酞胶囊治疗,研究组40例同时联合运用通窍活血汤治疗,采用MoCA量表评分评价认知功能,并比较两组改良Barthel指数评分。结果:治疗后研究组各项认知功能指标优于对照组(P<0.05)。治疗后,两组患者Barthel指数均高于治疗前,且研究组高于对照组(P<0.05),结论:在常规脑卒中二级预防等治疗基础上,采用通窍活血汤与丁苯酞胶囊联合用药,可显著提升卒中后血管性认知障碍患者的认知程度及自理能力。 Objective:To study the clinical effects of Tongqiao Huoxue Decoction and Butylphthalide Capsule in the treatment of post-stroke vascular cognitive impairment.Method:From March 2018 to May 2019,80 patients with post-stroke vascular cognitive impairment admitted to Neurology Department in our hospital were selected,and they were random divided into two groups.On regular basis,40 patients in the control group were treated with Butylphthalide Capsules,and 40 patients in the study group combined Tongqiao Huoxue Decoction.MOCA scale was used to evaluate cognitive function,and the modified Barthel index scores of the two groups were compared.Result:After treatment,the cognitive function of the study group was better than that of the control group(P<0.05).After treatment,the Barthel index of the two groups were higher than those before treatment,and which of the study group was higher than that of the control group(P<0.05).Conclusion:On the basis of routine secondary prevention of stroke,Tongqiao Huoxue Decoction combined with Butylphthalide Capsule can significantly improve the cognitive level and self-care ability of patients with vascular cognitive impairment after stroke.
作者 刘民胜 余伟雄 朱宝庆 LIU Minsheng;YU Weixiong;ZHU Baoqing(Meizhou Traditional Chinese Medicine Hospital,Meizhou 514500,China)
机构地区 梅州市中医医院
出处 《中外医学研究》 2020年第4期35-36,共2页 CHINESE AND FOREIGN MEDICAL RESEARCH
基金 梅州市科技计划项目(项目编号:171029212050728)
关键词 通窍活血汤 丁苯酞胶囊 卒中后血管性认知障碍 Tongqiao Huoxue Decoction Butylphthalide Capsule Vascular cognitive impairment after stroke
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