摘要
Although intelligent hydrogels have shown bright potential application in biomedical fields,they were prepared by conventional methods and still face many serious challenges,such as uncontrollable stimulus-response and low response sensitivity.Recently,RAFT polymerization provides a versatile strategy for the fabrication of intelligent hydrogels with improved stimulus-response properties,owing to the ability to efficiently construct hydrogel precursors with well-defined structure,such as block copolymer,graft copolymer,star copolymer.In this review,we summarized the recent progress on intelligent hydrogels based on RAFT polymerization with emphasis on their fabrication strategies and applications for controlled drug delivery.
Although intelligent hydrogels have shown bright potential application in biomedical fields, they were prepared by conventional methods and still face many serious challenges, such as uncontrollable stimulus-response and low response sensitivity. Recently, RAFT polymerization provides a versatile strategy for the fabrication of intelligent hydrogels with improved stimulus-response properties, owing to the ability to efficiently construct hydrogel precursors with well-defined structure, such as block copolymer, graft copolymer, star copolymer. In this review, we summarized the recent progress on intelligent hydrogels based on RAFT polymerization with emphasis on their fabrication strategies and applications for controlled drug delivery.
基金
supported by National Science and Technology Major Project of the Ministry of Science and Technology of China (No. 2018ZX10301402)
International Cooperation and Exchange of the National Natural Science Foundation of China (No. 51820105004)
the Science and Technology Program of Guangzhou (No. 201707010094)
Guangdong Innovative and Entrepreneurial Research Team Program (Nos. 2013S086 and 2016ZT06S029)
the Science and Technology Planning Project of Shenzhen (No. JCYJ20170307141438157)
