摘要
基于超声同时检测血流速度(U)和管腔直径(D)脉动变化的血流量-横截面积(QA)和直径-速度(ln(D)U)法是当前局域脉搏波速(PWV)检测的研究热点。通过仿真和临床实验系统比较了QA与ln(D)U方法的检测精度。对临床实测的颈动脉管腔半径和中心血流速度脉动变化,利用FIELDⅡ建立估计PWV的理论模型。30例仿真结果表明,QA法和ln(D)U法检测PWV与理论预设值的归一化均方根误差分别为0.30±0.08和0.45±0.13;两个年龄组20例临床结果表明,QA法和ln(D)U法对同一受试者连续两次颈动脉PWV检测的相关系数为0.94,变异系数分别为12.08V和13.17V。仿真和临床实验结果均表明QA法局域PWV的检测性能更好。
QA method and ln(D)U methods based on simultaneous measurements of Velocity(U)and arterial Diameter(D)using ultrasound technique are hotspots in the research of local Pulse Wave Velocity(PWV)detection.In present study,we do a comparative study on the accurate performance of QA and ln(D)U methods by the simulation and clinical trial systematically.According to the clinical measurements of carotid arterial wall displacement and central blood flow velocity during a cardiac cycle,an ultrasonic simulation model with preset theoretical value of PWV is established using FieldⅡplatform.The results based on 30 simulations show that the normalized root-mean-square-errors of estimated PWVs based on QA and ln(D)U methods are 0.30±0.08 and 0.45±0.13,respectively.Moreover,the results based on 20 human subjects show that the estimated PWVs using QA and ln(D)U are correlated with the coefficient of 0.94;the Coefficient of Variations(CV)are 12.08%and 13.17%,respectively.The simulation and clinical results verify that the QA method is more accurate to estimate local pulse wave velocities.
作者
赵伟佳
张榆锋
李支尧
陈建华
高莲
张俊华
ZHAO Weijia;ZHANG Yufeng;LI Zliiyao;CHEN Jianhua;GAO Lian;ZHANG Junhua(Province University Key Laboratory of Electronic Information Processing of High Altitude Medicine,Yunnan University,Kunming 650091;The Third A ffiliated Hospital of Kunming Medical University,Kunming 650031)
出处
《声学学报》
EI
CSCD
北大核心
2019年第6期1045-1052,共8页
Acta Acustica
基金
国家自然科学基金项目(81771928,61561049)资助
