摘要
目的探讨人感染巴贝虫的临床特征、实验室检查及治疗方法。方法回顾性分析首都医科大学附属北京友谊医院感染内科2017年8月28日收治的1例人感染巴贝虫并诱发噬血细胞综合征患者的病例资料和诊疗过程。结果患者长期居住于北京,无疫区疫水等接触史,但有河北农村生产劳作史,随后出现发热、口渴、多尿、水肿并伴有白细胞、红细胞、血小板计数减低,黄疸,血钠、血氯下降等;血涂片及骨髓涂片:可见红细胞胞内体,疑似巴贝虫感染;及时给予患者相应抗菌药物,加用克林霉素后患者所有症状消失及实验室指标恢复至正常。结论目前虽报道巴贝虫在我国北方蒙古边境、云南、东南沿海发病,但京津冀地区仍有部分散发病例,故尚需警惕,适时血涂片至关重要;巴贝虫感染亦可诱发噬血细胞综合征,易误诊为血液系统疾病,去除原发病是治疗关键。
Objective To investigate the clinical characteristics,laboratory examination and treatment of Babella infection.Methods Data of diagnosis and treatment of a patient infected with Babella and induced hemophagocytic syndrome in Beijing Friendship Hospital,Capital Medical University on August 28th,2017 were analyzed,retrospectively.Results The patient lived in Beijing and had no contact history of epidemic water,but had a history of labor in rural areas of Hebei Province,following by fever,thirst,polyuria,edema accompanied by decreased white blood cells,red blood cells,platelet count,blood sodium,jaundice and blood chlorine.Blood smear and bone marrow smear showed that erythrocyte endosomes and suspected Babesia infection.After timely administration of antibiotics and clindamycin,all the symptoms disappeared and laboratory indexes of the patient restored.Conclusions Although the disease is reported in Northern Mongolian border,Yunnan and Southeastern coast of China,but there are still some sporadic cases in Beijing-Tianjin-Hebei region,so we still should be vigilant about the disease,which is easy to be misdiagnosed as hematological diseases and timely blood smear is very important.
作者
王鹤
齐文杰
Wang He;Qi Wenjie(Department of Infection Medicine,Beijing Friendship Hospital Affiliated to Capital Medical University,Beijing 100050,China)
出处
《中华实验和临床感染病杂志（电子版）》
CAS
2019年第6期519-523,共5页
Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)
关键词
巴贝虫
发热待查
噬血细胞综合征
Babesia
Fever unknown original
Hemophagocytic syndrome
