摘要
目的比较幽门螺杆菌粪便抗原检测和血清幽门螺杆菌抗体胶体金试验对于诊断幽门螺杆菌感染的可用性和准确率。方法选择2018年8月1日—2019年5月30日在我院体检中心就诊的体检者共279例,分别进行血清HP抗体胶体金试验和幽门螺杆菌粪便抗原(HpSA)检测卡的检查。以HpSA阳性作为Hp现症感染诊断标准,从而对血清HP抗体胶体金试验诊断幽门螺杆菌感染的准确度、敏感性、特异性进行判断。结果 279例体检者中,血清Hp抗体胶体金试验检出Hp阳性164例,阳性率为58.78%;HpSA检出Hp阳性131例,阳性率为46.95%。以HpSA阳性作为Hp现症感染诊断标准,血清HP抗体胶体金试验的敏感性为98.47%、特异性为76.35%、阳性预测值为78.66%、阴性预测值为98.26%、准确度为86.74%。结论 HpSA检测和抗体胶体金试验均可作为一种快速简便、有效的幽门螺杆菌非侵入性检测手段。
Objective To determine the accuracy and availability of helicobacter pylori infection by comparing with Serum HP antibody colloidal gold test and Helicobacter pylori fecal antigen test.Methods A single blind study was performed.From August 1st,2018 to May 30th,2019,279 patients were examined by Serum Hp antibody colloidal gold and Helicobacter pylori stool antigen(HpSA)test cards.HpSA positive was used as the diagnostic criteria for Hp infection.so as to determine the accuracy,sensitivity and specificity of Hp antibody gold test in diagnosing helicobacter pylori infection.Results Among 279 physical examinations,164 were positive for Hp by Serum Hp antibody colloidal gold(58.78%)and 131 were positive for Hp by HpSA(46.95%).HpSA positive was used as the diagnostic criteria for Hp infection,and the sensitivity,specificity,positive predictive value,negative predictive value and accuracy of serum HP antibody gold test were 98.47%76.35%78.66%98.26%and 86.74%,respectively.Conclusion HpSA test and antibody gold test can be used as a fast,simple and effective non-invasive test for helicobacter pylori.
作者
林美梅
LIN Meimei(Department of Physical Examination,The First Affiliated Hospital of Xiamen University,Xiamen Fujian 361003,China)
出处
《中国卫生标准管理》
2019年第24期103-106,共4页
China Health Standard Management
关键词
消化不良
幽门螺杆菌
血清Hp抗体胶体金试验
幽门螺杆菌粪便抗原检测
前瞻性研究
敏感性
阴性预测值
indigestion
helicobacter pylori
serum Hp antibody colloidal gold test
helicobacter pylori stool antigen detection
prospective study
sensitivity
negative predictive value
