摘要
轮状病毒是引起儿童和幼龄动物急性胃肠炎的主要病因之一,在世界范围内广泛存在,是一种重要的人兽共患病病原。猪轮状病毒是引起哺乳仔猪和断奶仔猪急性胃肠炎的主要病原之一,有复杂的病原流行病学特征和遗传多样性。目前尚无针对该病的有效治疗药物,疫苗接种仍是防控该病的主要措施。掌握猪轮状病毒的分子流行动态,可对诊断猪轮状病毒病和新型疫苗的研究提供科学依据。论文对猪轮状病毒的病原和分子流行病学调查结果进行了综述,旨在阐述不同地理区域中猪轮状病毒的流行特点,为进一步开展猪轮状病毒病原研究及后期疫苗和药物的研制提供参考。
Rotavirus(RV) is an important zoonotic pathogen and a major cause of acute viral gastroenteritis in young animals and children worldwide.Porcine rotavirus is a major cause of acute gastroenteritis in nursing and weaned piglets,with complicated etiology,epidemiology and high genetic diversity.There are no effective therapeutic drugs to treat it,and vaccination is the efficiency method to prevent and control it.Mastering the molecular dynamics of porcine rotavirus will provide a scientific basis for the diagnosis of rotavirus disease and the research of new vaccine.In this review,we summarized previous and recent research of etiology and epidemiology to provide insights on historic and current prevalence and genetic diversity of porcine rotavirus in different geographic regions,and provide reference for the development of vaccines and drugs.
作者
苗艳
朱庆贺
陈亮
李丹
李阳
兰世捷
徐馨
史同瑞
MIAO Yan;ZHU Qing-he;CHEN Liang;LI Dan;LI Yang;LAN Shi-jie;XU Xin;SHI Tong-rui(Animal Husbandry and Veterinary Institute,Heilongjiang Academy of Agricultural Sciences,Qiqihar,Heilongjiang,161000,China)
出处
《动物医学进展》
北大核心
2020年第1期93-97,共5页
Progress In Veterinary Medicine
