摘要
目的:探讨血清FT3、T3、TSH、同型半胱氨酸(Hcy)及B型脑钠肽(BNP)水平在急性心肌梗死患者中的临床价值。方法:选取2017年1月-2018年12月笔者所在医院收治的急性心肌梗死患者135例为心梗组,1周后评估患者心功能;同时设60例健康人群为对照组,观察血清Hcy、BNP、甲状腺激素水平,分析Hcy、BNP及甲状腺激素水平之间的相关性,评估血清甲状腺激素水平预测心梗后心衰发生的敏感性和特异性。结果:与对照组比较,心梗阻血清FT3、T3较低,Hcy、BNP较高,差异均有统计学意义(P<0.01);在急性心梗患者组中,血清Hcy与BNP呈正相关(r=0.869,P<0.01);血清FT3、血清T3与BNP呈负相关(r=-0.612、-0.503,P<0.01);血清FT3水平对于预测其后心衰发生的AUC 0.832,T3的AUC为0.768。结论:血清Hcy、BNP、甲状腺激素水平在急性心肌梗死患者诊断治疗中有很重要的临床价值,血清FT3,T3对心梗后心衰的发生有预测价值。
Objective:To explore the clinical value of serum FT3,T3,TSH,homocysteine(Hcy)and B-type brain natriuretic peptide(BNP)levels in patients with acute myocardial infarction.Method:To observe the levels of serum Hcy,BNP and thyroid hormone in 135 patients with acute myocardial infarction admitted to our hospital from January 2017 to December 2018,and to evaluate cardiac function one week later,to analyze the correlation between Hcy,BNP and thyroid hormone levels,and to evaluate the sensitivity and specificity of serum thyroid hormone levels in predicting the occurrence of heart failure after myocardial infarction.60 healthy people as control group.Result:Compared with the control group,the serum FT3,T3 in patients with heart obstruction were lower,Hcy and BNP were higher,the differences were statistically significant(P<0.01).In patients with acute myocardial infarction,serum Hcy was positively correlated with BNP(r=0.869,P<0.01).Serum FT3 and T3 were negatively correlated with BNP(r=-0.612,-0.503,P<0.01).Serum FT3 level was a predictor of subsequent heart failure,and AUC of FT3 was 0.832,AUC of T3 was 0.768.Conclusion:Serum Hcy,BNP and thyroid hormone levels have important clinical value in the diagnosis and treatment of acute myocardial infarction.Serum FT3 and T3 have predictive value in the occurrence of heart failure after myocardial infarction.
作者
王伟涛
WANG Weitao(Mentougou District Hospital of Beijing,Beijing 102300,China)
出处
《中外医学研究》
2019年第34期81-83,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
