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脓毒症患儿检验中D-二聚体和降钙素原的临床意义 被引量:3

Clinical Significance of D-dimer and Procalcitonin in Children with Sepsis
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摘要 目的:探析脓毒症患儿临床检验中D-二聚体及降钙素原的临床应用价值。方法:以2017年4月-2018年6月为研究时段,将笔者所在医院接收的62例脓毒症患儿作为试验组,其中重度脓毒症35例,轻度脓毒症27例,同期另选取到笔者所在医院行健康检查的健康儿童56例作为对照组。对两组儿童降钙素原、D-二聚体水平进行检测,并对研究组重度与轻度脓毒症患儿降钙素原、D-二聚体水平进行分析。结果:试验组降钙素原、D-二聚体水平均高于对照组,差异有统计学意义(P<0.05)。试验组重度脓毒症患儿降钙素原、D-二聚体水平均高于轻度患儿,差异有统计学意义(P<0.05)。结论:在患儿血清中,降钙素原、D-二聚体水平的高低能有效地反映脓毒症的病症严重程度情况,对后期的治疗工作提供数据支持。 Objective:To explore the clinical value of D-dimer and procalcitonin in clinical test of children with sepsis.Method:From April 2017 to June 2018,62 children with sepsis received in our hospital were selected as the experimental group,including 35 cases with severe sepsis and 27 cases with mild sepsis.In the same period,56 healthy children who underwent health examination in our hospital were selected as the control group.The levels of procalcitonin and D-dimer in children of the two groups were tested,and the levels of procalcitonin and D-dimer in children with severe and mild sepsis were analyzed.Result:The levels of procalcitonin and D-dimer in the experimental group were higher than those in the control group,and the differences were statistically significant(P<0.05).The levels of procalcitonin and D-dimer in severe sepsis in the experimental group were higher than those in mild sepsis,the differences were statistically significant(P<0.05).Conclusion:In the serum of children,the level of procalcitonin and D-dimer can effectively reflect the severity of sepsis and provide data support for the later treatment.
作者 卓媛媛 ZHUO Yuanyuan(Zhongshan Hospital Affiliated to Xiamen University,Xiamen 361000,China)
出处 《中外医学研究》 2019年第34期61-62,共2页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 患儿 降钙素原 D- 二聚体 脓毒症 临床诊断 Children Procalcitonin D-dimer Sepsis Clinical diagnosis
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