摘要
目的:分析妊娠期妇女B族链球菌(GBS)感染情况及GBS感染对母儿预后的影响。方法:选取2018年1月-2019年1月笔者所在医院产科接受产检及分娩的妊娠早期(孕龄8~12周)单活胎孕妇2800例,为A组,取阴道下1/3分泌物进行GBS检测;待孕龄至12~28周到笔者所在医院进行复查,为B组(2314例);待孕龄至28周以上再次到笔者所在医院进行复查,为C组(2218例);比较三组间GBS阳性率。根据C组的GBS感染情况分为GBS阳性组(201例)、GBS阴性组(2017例),比较两组间围生期母儿的预后。结果:A、B、C组GBS阳性率分别为5.43%、5.88%、9.66%,且C组孕妇的GBS阳性率显著高于A、B组(P<0.05);GBS阳性组早产、胎膜早破、宫内感染、剖宫产及产后出血的发生率显著高于GBS阴性组(P<0.05);GBS阳性组新生儿窒息、新生儿感染、新生儿肺炎及新生儿低体重的发生率显著高于GBS阴性组(P<0.05)。结论:妊娠晚期妇女感染GBS的几率更高,妊娠晚期妇女感染GBS对母婴带来严重不良预后。
Objective:To analyze the infection of group B Streptococcus(GBS)in pregnant women and the influence of GBS infection on the prognosis of mothers and infants.Method:From January 2018 to January 2019,2800 women with single live births(8-12 weeks gestational age)in the early stage of pregnancy in our hospital were selected as group A.One third of vaginal secretions were taken for GBS detection,from 12 to 28 weeks gestational age to our hospital for reexamination,group B(2314 cases),and from 28 weeks gestational age to more to our hospital for reexamination,group C(2218 cases).The positive rate of GBS was compared among the three groups.According to the GBS infection in group C,the patients were divided into GBS positive group(201 cases)and GBS negative group(2017 cases).The prognosis of perinatal mothers and infants was compared between the two groups.Result:The positive rates of GBS in group A,B and C were 5.43%,5.88%and 9.66%respectively,and the positive rates of GBS in group C were significantly higher than those in group A and B(P<0.05).The incidence of premature delivery,premature rupture of membranes,intrauterine infection,cesarean section and postpartum hemorrhage in group GBS positive were significantly higher than those in group GBS negative(P<0.05).The incidence of infection,neonatal pneumonia and low birth weight was significantly higher than that of GBS negative group(P<0.05).Conclusion:Women in the third trimester of pregnancy are more likely to be infected with GBS.Infection of GBS in women in the third trimester of pregnancy brings serious adverse prognosis to mothers and infants.
作者
洪佳芬
苏玩琼
倪洁珊
HONG Jiafen;SU Wanqiong;NI Jieshan(Jieyang Rongcheng District Maternal and Child Health Hospital,Jieyang 522000,China)
出处
《中外医学研究》
2019年第36期7-9,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
基金
揭阳市卫生健康局医学科学研究项目（项目编号：揭市卫（2019)66号-105）
