摘要
目的探讨B族溶血性链球菌(GBS)对围生期感染的影响。方法采用3%TH肉汤增菌液体培养基检测GBS,ELISA方法检测抗GBSⅢ型荚膜多糖抗体IgG水平。结果①孕妇GBS带菌率为10.12%(166/1642),新生儿带菌率为9.95%(20/201)。②孕妇阴道GBS带菌对不良产科并发症及新生儿预后无明显影响。③孕妇GBS阳性与阴性者的IgG浓度分别为(1.59±0.74)mg/L、(3.94±2.36)mg/L(P<0.001);新生儿IgG浓度分别为(1.14±0.69)mg/L、(3.04±1.82)mg/L(P<0.001)。结论GBS带菌对母婴预后影响不大。
Objective To study the influence and the reasons of perinatal infection of the group B streptococcus (GBS) by investigating the vaginal colonization in the pregnant women. Methods 3%TH selective broth media was used for culture of GBS and ELISA for protecting GBS Ⅲ IgG antibody. Results ① The GBS carrier rate in 1642 pregnant women was 10.12%(166/1642), and 9.95%(20/201 ) in newborns. ② Obstetric complications and neonatal prognosis associated with GBS carrier were similar with those of non-carrier. ③ The IgG value in carrier and non-carrier mothers was (1.59±0.74)mg/L and (3.94±2.36)mg/L respectively (P〈0.O01); while that in newborns was (1.14±0.69)mg/L and (3.04±1.82)mg/L respectively (P〈0.001). Conclusions GBS is not severe enough to threat the health of pregnant women and their newborns.
出处
《北京医学》
CAS
2005年第9期516-518,共3页
Beijing Medical Journal
基金
国家九五攻关基金资助项目(编号969040607)