摘要
目的探讨腹腔镜辅助全胃切除术应用于不同年龄段进展期胃癌患者治疗中的临床价值。方法回顾性分析2010年1月至2013年12月93例进展期胃癌患者资料,根据年龄差异将其分为A、B、C三组,每组31例,所有患者均行腹腔镜辅助全胃切除术治疗。A组平均年龄(48.6±7.6)岁;B组平均年龄(72.3±5.1)岁;C组平均年龄(83.2±2.2)岁。采用统计学软件SPSS19.0处理数据,围手术指标等用(x±s)表示,F检验;术后并发症等采用χ2检验;Kapln-Meier法绘制三组患者术后无病生存曲线图和总生存率曲线图;P<0.05为差异有统计学意义。结果三组患者在围术期手术时间、出血量、淋巴结清扫、恢复排气时间、住院时间等方面差异无统计学意义(P>0.05);A、B、C三组患者术后总并发症发生率(22.6%vs.25.8%vs.29.0%)比较,组间差异无统计学意义(P>0.05),但肺部感染率C组>B组>A组(P<0.05);三组患者术后5年内的无病生存率和总生存率差异无统计学意义(P>0.05)。结论不同年龄段进展期胃癌患者行腹腔镜辅助全胃切除术治疗术中安全,疗效近似,可适用于老年尤其是高龄患者。
Objective To investigate the clinical value of laparoscopic assisted total gastrectomy in the treatment of patients with advanced gastric cancer at different ages.Methods From January 2010 to December 2013,clinical data of 93 patients with advanced gastric cancer were retrospectively analyzed.According to age differences,the patients were divided into group A,group B and group C,with 31 patients in each group.All the patients received laparoscopic assisted total gastrectomy.The average age of group A was 48.6±7.6 years.The average age of group B was 72.3±5.1 years.The average age of group C was 83.2±2.2 years.Statistical analysis were performed by using SPSS19.0 software.Measurement data,such as perioperative indicators were expressed as(x±s),and were examined by using F test.Count data such as complication rates were examined by chi square test.Postoperative disease-free survival and overall survival were analyzed by using Kaplan Meier method.A P value<0.05 was considered as statistically significant difference.Results There were no statistically significant differences among the three groups in terms of operation time,blood loss,harvested lymph nodes,recovery of exhaust time,hospitalization time.(P>0.05).The total incidence of postoperative complications in the three groups were 22.58%,25.80%and 29.03%respectively,with no significant difference(P>0.05),however the lung infection rate in group C>group B>group A were shown(P<0.05).There were no significant difference in terms of disease-free survival rate and overall survival rate among three groups within 5 years after surgery(P>0.05).Conclusion Laparoscopic assisted total gastrectomy is safe and effective in the treatment of advanced gastric cancer in different age groups.
作者
孙伟
曹祥龙
Sun Wei;Cao Xianglong(Department of general surgery,Pinggu hospital,Beijing hospital of Traditional Chinese Medicine,Beijing 101200,China;Department of gastrointestinal surgery,Beijing hospital,Beijing 100730,China)
出处
《中华普外科手术学杂志（电子版）》
2020年第1期24-27,共4页
Chinese Journal of Operative Procedures of General Surgery(Electronic Edition)
基金
国家自然科学基金项目(81660703)~~
关键词
胃肿瘤
腹腔镜
胃切除术
疗效比较研究
Stomach neoplasms
Laparoscopes
Gastrectomy
Comparative effectiveness research
