摘要
目的分析血TGF-β水平检测对热射病患者预后判断的价值。方法将46例热射病患者按预后情况分为存活组(n=28)和死亡组(n=18)。患者均接受常规治疗并进行实验室检查。对比两组入院时各检查指标、APACHEⅡ、GCS评分以及不同时间的血TGF-β水平。结果入院时,存活组体温、Hb、MYO水平、APACHEⅡ评分明显低于死亡组,PCT水平、GCS评分明显高于死亡组,PT明显短于死亡组(P<0.05)。存活组入院时、入院后1、3、6 h的血TGF-β水平均高于死亡组(P<0.05)。结论血TGF-β水平越低,热射病患者预后效果越差,临床可以根据热射病患者入院时血TGF-β水平对其预后进行判断,以此制定针对性预防和治疗措施,确保患者安全。
Objective To analyze the value of blood TGF-βlevel detection in prognosis judgement of patients with heat stroke.Methods Forty-six patients with heat stroke were divided into survival group(n=28)and death group(n=18)according to the prognosis.All patients received routine treatment and laboratory examination.The examination indexes,APACHEⅡand GCS scores at admission and blood TGF-βlevels at different time were compared between the two groups.Results At admission,body temperature,the levels of Hb,MYO and APACHEⅡscore in the survival group were significantly lower than those in the death group,PCT level and GCS score were significantly higher than those in the death group,PT was significantly shorter than that in the death group(P<0.05).The levels of blood TGF-βin the survival group were higher than those in the death group at admission and at 1,3,6 hours after admission(P<0.05).Conclusion The lower the blood TGF-βlevel,the worse the prognosis of patients with heat stroke,and the clinical prognosis can be judged according to the blood TGF-βlevel of patients with heat stroke at admission,so as to develop targeted prevention and treatment measures to ensure patients'safety.
作者
徐少丽
马骥
兰乃祥
李鹤云
付峰
冯静
XU Shao-li;MA Ji;LAN Nai-xiang;LI He-yun;FU Feng;FENG Jing(No.215 Hospital of Shaanxi Nuclear Industry,Xianyang 712000,China)
出处
《临床医学研究与实践》
2020年第1期42-43,共2页
Clinical Research and Practice
基金
教育部科技发展中心项目(No.201836000G150084)
