摘要
作为一种天然稳定剂的双糖,海藻糖(Trehalose)在逆境下对生物体活性的保护功能既吸引了广泛的研究兴趣,也使其具有良好的应用价值和潜力。本文聚焦重要模式微生物和工业应用微生物酵母,结合组学研究最新进展,从海藻糖代谢途径、应激条件下的海藻糖代谢和转录特征以及提高胞内海藻糖含量策略等方面,对内源性海藻糖研究新进展进行了综述。
As a naturally stable disaccharide, the protective function of trehalose on the activity of organisms under adverse conditions has attracted a wide range of research interests, and also has good application value and potential. This paper focuses on the important model microorganisms and industrial applied yeast, combined with the latest progress in the research of omics, and summarizes the new progress in the research of endogenous trehalose from the aspects of trehalose metabolic pathway, trehalose metabolism and transcription characteristics under stress conditions, and the strategy of improving intracellular trehalose.
作者
陈敦武
陈雄
李欣
Dunwu Chen;Xiong Chen;Xin Li(Key Laboratory of Fermentation Engineering(Ministry of Education),Hubei Collaborative Innovation Center for Industrial Fermentation,School of Food and Biological Engineering,Hubei University of Technology,Wuhan 430068,Hubei Province,China)
出处
《微生物学报》
CAS
CSCD
北大核心
2019年第12期2276-2284,共9页
Acta Microbiologica Sinica
基金
国家自然科学基金(31871789)
湖北省教育厅青年基金(6101-12131)~~
关键词
酵母
内源性海藻糖
代谢组
转录组
yeast
endogenous trehalose
metabolomics
transcriptomics
