摘要
测定了四对新合成的四氢β-咔啉化合物的~13C NMR谱,通过APT,HETCOR和HETCOLOC谱指认了所有碳的归属.所确定的化学位移规律可以用来确定它们的构型.
13C NMR spectra for the four pairs of new tetrahydro-β-carbolines are reported . Chemical shift assignments have been made for all carbons of the tetrahydro-β-carbolincs by APT, HETCOR & HETCOLOC spectra. The chemical shifts of 5-C & 6 -C can be used for configurational assignments of tetrahydro - β - carbolines, for 5-C & 6-C chemical shifts are easily recongnizable. The downfield one is assigned to 5-C & the upfield one assigned to 6-C. In the spectra of 3a, b & 4a, b, both 3-C & 5-C undergo downfield shifts, compared with the corresponding carbons of la, b & 2a, b. Meanwile, 2 -C & 6-C undergo upfield shifts, presumably owing to slight difference in polarization of the C -N bonding electrons.
出处
《波谱学杂志》
CAS
CSCD
1992年第2期183-188,共6页
Chinese Journal of Magnetic Resonance
关键词
咔啉
NMR
构型
吲哚
生物碱
Tetrahydro-β-carboline
13C NMR
Configuration
