摘要
目的 探讨腹水端粒酶对良性和恶性腹水的鉴别诊断价值。方法 经临床、生化、影像、病理等方法,将32例腹水患者分为良性腹水组19例和恶性腹水组13例,抽取腹水,用TRAP检测其端粒酶活性以及腹水AFP、腹水细胞学检查。结果 恶性腹水中端粒酶、AFP及肿瘤细胞阳性率均显著高于良性腹水组(P值均<0.01);与AFP及肿瘤细胞相比腹水端粒酶检测具有较高的敏感性(71.8％)和特异性(94.7％),且具有良好的稳定性。结论 腹水端粒酶测定对鉴别腹水性质具有较高的敏感性及特异性,且稳定性好,对腹水性质的鉴别有良好的使用价值。
Objective To explore the differential diagnosis value of telomere ferment to benign and malignant ascites. Method Ascites were drawn and examined with TRAP to test the telomere ferment and with ascites AFP and ascites cytology by ways of clinic, biochemistry and pathology of benign ascites group(19 cases) and malignant ascites group(13 cases) . Result Rates of telomere ferment, AFP and tumor cell positive were significantly higher in malignant group than those in benign group(p <0. 01) . Compared with AFP and tumor cell, telomere ferment test had higher sensitivity (71. 8% ), specificity (94. 7% ) and stability. Conclusion Telomere ferment test has high sensitivity, specificity and stablity and is good for differentiation of ascites.
出处
《湖北民族学院学报（医学版）》
2002年第3期12-14,共3页
Journal of Hubei Minzu University(Medical Edition)
关键词
端粒酶
腹水
鉴别诊断
telomere ferment
ascites
differential diagnosis
