摘要
目的 对血清TRACP5b作为骨吸收生化标志物进行临床研究。方法 利用BoneTRAP试剂盒 ,对 473例正常及骨质疏松患者血清做TRACP5b检测及分析。结果 男性和女性 ,随年龄的增加 ,特别是男性更年期及女性绝经期后 ,血清TRACP5b水平均不断升高 ,表明骨吸收增强 ;当患有骨质疏松后 ,血清中TRACP5b的水平高于同龄人 ,且男性及女性骨质疏松患者血清TRACP5b水平均高于正常人 ,统计学提示有显著性差异。
Objective\ Clinical study of serum tartarte resistant acid phosphatase5b as bone resorption biochemical marker. Methods\ Determination of the serum TRACP5b level in 473 person,including normal and patients,by the bone TRAP kit. Results\ The serum TRACP5b level of men and women are increased in old person,especially climacteric or menopause later,which indicates that the bone resorption are improved.Simultaneously,statistically significant difference exists between normal and osteoporosis patients. Conclusion\ Serum TRACP5b is a specificity marker in monitoring bone resorption.\;
出处
《中国骨质疏松杂志》
CAS
CSCD
2002年第4期331-332,336,共3页
Chinese Journal of Osteoporosis
