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血管紧张素Ⅱ1型受体与高血压左心室重构 被引量:13

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摘要 左心室重构是高血压病重要的病理生理过程 ,包括心肌细胞肥大和心肌间质重塑两个方面。血管紧张素Ⅱ及其它激素、细胞因子等共同组成的神经—内分泌—细胞因子网络对左心室重构的形成起着调控作用。在这个过程中 ,血管紧张素Ⅱ 1型受体联系着细胞间和细胞内各种信息的传递和沟通 ,成为重构形成的桥梁 ;同时 ,该受体的遗传背景可能引起受体功能的变化并影响左心室重构的表型 ,对个体化治疗和预防有潜在意义。
作者 方明 彭健
出处 《中国动脉硬化杂志》 CAS CSCD 2002年第5期457-460,共4页 Chinese Journal of Arteriosclerosis
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