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奥曲肽治疗急性胰腺炎疗效研究 被引量:4

Study of curative effects of octreotide in treating acute pancreatitis
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摘要 目的 比较奥曲肽与常规治疗急性胰腺炎的疗效。方法  5 5例急性胰腺炎 (重型 11例、水肿型 4 4例 )分为两组 ,对照组 2 8例为常规治疗 ,治疗组 2 7例同时用奥曲肽 0 .1mg加入 5 %葡萄糖注射液 2 5 0ml静脉滴注 ,q8h ,或奥曲肽 0 1mg皮下注射 ,q8h ,均至腹痛消失 ,血尿淀粉酶恢复正常停药。 结果 急性水肿型胰腺炎腹痛消失 ,血、尿淀粉酶、体温恢复时间联用药组较对照组短 ,治疗急性重症胰腺炎时 ,奥曲肽组的手术率、并发症发生率、死亡率较常规治疗组明显降低。结论 奥曲肽为主的内科治疗对急性重症胰腺炎有较好的疗效 。 Objective To compare the curative effects of acute pancreatitis with octreotide and routine treatment.Methods 55 cases of acute pancreatitis(severe type in 11,edematous type in 44)were divided into 2 groups.The control group in 28 were routine treatment.The octoreotide group in 27 were given simultaneously 0.1mg octreotide in 5% glucose injection 250ml,iv drip,q8h,or with octreot q8h.The patients of the 2 groups stopped the therapy when all the symptoms had disappeared and the amylases in blood and urine had turned to be normal.Results The time of abdominal pain disappeared and of amylases in blood and urine,body temperature recovered of acute edematous pancreatitis was shorter compared with the control group.When the acute severe pancreatitis was treated,the operative rate,the incidence rate of complications and the mortality of the group of octreotide were reduced obviously compared with the routine treatment group.Conclusion The comprehensive treatments of octreotide have better curative effects to acute severe pancreatitis and can reduce the incidence rate of complications and the mortality of it.
作者 葛丽娟
出处 《中国基层医药》 CAS 2002年第11期1003-1004,共2页 Chinese Journal of Primary Medicine and Pharmacy
关键词 急性胰腺炎 奥曲肽 治疗方法 疗效 Acute pancreatitis Octreotide
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