摘要
１ＩｎｔｒｏｄｕｃｔｉｏｎＩｔｉｓｏｂｖｉｏｕｓｔｈａｔｎｏｒｍａｌｐｈａｒｍａｃｏｋｉｎｅｔｉｃｓｍｏｄｅｌ，ｓｕｃｈａｓｔｈｅｃｏｍｐａｒｔｍｅｎｔｍｏｄｅｌ，ｃａｎｏｎｌｙｄｅｓｃｒｉｂｅｐｈａｒｍａｃｅｕｔｉｃａｌｓ’ｐｈａｒｍａｃｏｋｉｎｅ...
Rate constants are important pharmacokinetic parameters and very useful in study of radiopharmaceuticals, nuclide therapy and internal radiation. In the situation of small number of compartments, solution of rate constants is not too difficult. But with increasing compartment number, the calculation is tending to more complex, which makes solving rate constants very difficult. Therefore, according to a general principle a series of formulae is established to simplify the process of solving rate constants.
