摘要
目的 研究卷丹 (LiliumlancifoliumThunb .)鳞叶的化学成分。方法 用各种色谱技术进行分离和纯化 ,用MALDI TOF MS ,HR SI MS ,IR ,1 HNMR ,1 3CNMR ,DEPT ,1 H 1 HCOSY ,HMQC和HMBC等光谱和波谱技术鉴定其结构。结果 从卷丹鳞叶中分得 2个甾体皂苷 ,鉴定化合物 1为薯蓣皂苷元 3 O {O α L 鼠李糖基 (1→ 2 ) O [β D 木糖基(1→ 3) ] β D 葡萄糖苷 ,化合物 2为薯蓣皂苷元 3 O {O α L 鼠李糖基 (1→ 2 ) O [α L 阿拉伯糖基 (1→ 3) ] β D 葡萄糖苷。结论 化合物 2为新化合物 ,命名为卷丹皂苷A。
AIM To investigate the chemical constituents of the bulbs ofLilium lancifolium Thunb.. METHODS Various chromatographic techniques were used to isolate the chemical constituents. MALDI-TOF-MS, HR-SI-MS, IR, ~1HNMR, ~ 13CNMR, DEPT, ~1H- ~1H COSY, HMQC and HMBC were used to determine the structures of the isolated constituents. RESULTS Ophiopogonin D′ and lililancifoloside A were isolated from the bulbs ofLilium lancifolium Thunb., and were identified as diosgenin 3-O-{O-α-L-rhamnopyranosyl-(1→2)-O-[β-D-xylopyranosyl(1→3)]-β-D-glucopyranoside} and diosgenin 3-O-{O-α-L-rhamnopyranosyl-(1→2)-O-[α-L-arabinopyranosyl(1→3)]-β-D-glucopyranoside}, respectively. CONCLUSION Ophiopogonin D′ was isolated from the bulbs ofLilium lancifolium Thunb. for the first time. Lililancifoloside A is a new steroidal saponin.
出处
《药学学报》
CAS
CSCD
北大核心
2002年第11期863-866,共4页
Acta Pharmaceutica Sinica
基金
国家"九五"科技攻关资助项目 (96 90 1 0 6 49) .
关键词
卷丹
甾体皂苷
分离
鉴定
麦冬皂苷D'
卷丹皂苷A
Lilium lancifolium Thunb.
steroidal saponin
ophiopogonin D′
lililancifoloside A
