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卵巢早衰:基因与免疫 被引量:7

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摘要 卵巢早衰(POF)是指发生在40岁以前的自然绝经,其发生率在1%~2%,病因不明。目前认为,卵巢早衰是一种异源性疾病,其病因包括X染色体异常,免疫,感染,医源性因素(手术,放化疗),促性腺激素及受体缺陷等。近年来,研究多集中在基因和免疫方面,认为是基因或免疫缺陷所致,综述卵巢早衰与基因、免疫的关系。
作者 秦姗 沈鸿敏
出处 《国外医学(计划生育分册)》 2002年第4期222-225,共4页
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