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同种输血可能是心脏术后感染的因素之一 被引量:2

Allogeneic blood transfusions may be one of the factors of postoperative infection in patients undergoing cardiovascular surgery
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摘要 目的 探讨同种输血和输血量与心脏手术术后感染的相关性。方法 选择 12岁以上心脏病人 2 6 6例 ,在静吸复合麻醉、低温心肺转流下行心脏外科手术。根据是否输用同种血和输血量分成三组 :A组 (n =71)为对照组 ,无同种输血 ;B组 (n =5 1)同种输血量≤ 4 0 0ml;C组 (n =14 4 )同种输血量≥ 80 0ml。对三组病例术后感染情况进行分析比较。结果 A组术后感染 2例 (2 81% ) ,B组感染 12例 (2 3 6 % ) ,C组感染 37例 (2 5 6 % ) ,B、C组感染率显著高于A组 (P <0 0 1)。结论 同种输血是心脏手术术后感染的危险因素之一 ,但是否是感染独立的相关因素尚需进一步研究。 Objective To examine the relation of infection with allogeneic blood transfusion and transfusion volume after cardiovascular surgery.Method 266 patients,12 years of age or older,were scheduled for elective cardiovascular surgeries under venous inhalation complex anesthesia and hypothermia cardiopulmonary bypass.Based on whether receiving allogeneic blood transfusion or not and transfusion volume,they were divided into three groups.Group A( n= 71):no allogeneic blood transfusion,as a controlled group;Group B ( n= 51):transfusion volume ≤400ml;Group C ( n= 144):transfusion volume≥800ml.The postoperative infections among three groups were compared and analysed.Result The study showed that 2 cases(2 81%),12 cases (23 6%) and 37 casese (25 6%)had postoperative infection in group A,B and C respectively.The infection rate in group B,C was significantly higher than that in group A( P< 0 01).Conclusion Allogeneic blood transfusion and transfusion volume may be one of the risk factors of postoperative infection in patients undergoing cardiovascular surgeries,but if it is an isolated relative factor of infection needs further investigations. [
出处 《临床麻醉学杂志》 CAS CSCD 2002年第10期523-524,共2页 Journal of Clinical Anesthesiology
关键词 同种输血 术后感染 心脏手术 危险因素 Allogeneic blood transfusion Postoperative infection Cardiovascular surgery
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参考文献4

  • 1Despotis G.Current and evolving issues in transfusion therapy.51st Annual refresher Couse lectures.San Francisco,CA,USA.2000.262.
  • 2Blumberg N,Triulzi DJ,Heal JM.Transfusion induced immunomodulation and its clinical conseqence.Tansfusion Med Red,1990,4:24.
  • 3Dzik WH.Effects on recipients of exposure to allogeneic donor leukocytes.J Clin Apheresis,1994,9:135.
  • 4Crosby E.Effects of transfusion on immune function.12th World Congress of Anesthesiologists(WCA)Book of proceedings,Montreal:Canada.2000.92-93.

同被引文献22

  • 1陈龙,张冯江,胡双飞,严敏.同种异体输血及自体血回输在脊柱手术围术期的预测因素[J].中国老年学杂志,2014,34(6):1476-1479. 被引量:12
  • 2陈方祥 刘怀琼 等.体腔血自体回输与凝血纤溶功能的变化[J].中华麻醉学杂志,1998,18(2):82-83.
  • 3Kimura N,Toyoki Y,Ishido K,et al.Perioperative blood transfusion as a poor prognostic factor after aggressive surgical resection for hilar cholangiocarcinoma[J].J Gastrointest Surg,2015,19(5):866-879.
  • 4Chen A,Trivedi AN,Jiang L,et al.Hospital blood transfusion patterns during major noncardiac surgery and surgical mortality[J].Medicine(Baltimore),2015,94(32):e1342.
  • 5Subramanian V,Bharat A,Vachharajani N,et al.Perioperative blood transfusion affects hepatitis C virus(HCV)-specific immune responses and outcome following liver transplantation in HCV-infected patients[J].HPB(Oxford),2014,16(3):282-294.
  • 6Cata JP,Chukka V,Wang H,et al.Perioperative blood transfusions and survival in patients with non-small cell lung cancer:a retrospective study[J].BMC Anesthesiol,2013,13(1):42.
  • 7Wei C,Yu Y,Chen Y,et al.Impact of warming blood transfusion and infusion toward cerebral oxygen metabolism and cognitive recovery in the perioperative period of elderly knee replacement[J].J Orthop Surg Res,2014(9):8.
  • 8Meier J,Müller MM,Lauscher P,et al.Perioperative red blood cell transfusion:harmful or beneficial to the patient[J].Transfus Med Hemother,2012,39(2):98-103.
  • 9Pandey P,Chaudhary R,Aggarwal A,et al.Transfusion-associated immunomodulation:quantitative changes in cytokines as ameasure of immune responsiveness after one time blood transfusion in neurosurgery patients[J].Asian J Transfus Sci,2010,4(2):78-85.
  • 10邓硕曾,纪宏文,刘进.体外循环实施血液保护技术两年少输血60余万毫升(附不输血心脏手术225例分析)[J].临床麻醉学杂志,1998,14(4):233-234. 被引量:28

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