摘要
目的探究凝血四项并血脂检验在糖尿病患者检查中的临床作用。方法 67例研究对象选取自2016年11月-2017年10月间来该院接受治疗的糖尿病患者,将其作为试验组。试验组中根据患者有无并发症再分为并发症组(33例)和未并发组(34例)。选取同期来该院体检的67名健康者为对照组,两组分别进行凝血四项检查和血脂检验,比较检验结果。结果试验组的凝血四项(PT、APTT、FIB、 TT)检查结果与对照组间差异有统计学意义(t=15.642 4、8.087 4、16.000 6、32.789 0,P<0.05)。试验组平均PT含量(10.63±0.62)s、平均APTT含量(28.70±5.21)s、平均FIB含量(4.63±0.78)g/L、平均TT含量(13.39±0.57)s。试验组患者表现为高凝血倾向。并发组与未并发组患者的PT、TT和APTT含量间差异无统计学意义(P>0.05),并发组患者的FIB水平明显高于未并发组,差异有统计学意义(t=9.729 6,P=0.000 0)。试验组平均TC含量(5.41±1.31)mmol/L、平均TG含量(3.20±1.43)mmol/L、平均HDL-C含量(1.18±0.51)mmol/L、平均LDL-C含量(3.15±1.39)mmol/L。试验组的血脂检验(TC、TG、HDL-C、LDL-C)结果与对照组间差异有统计学意义(t=3.846 9、6.964 2、6.389 7、4.706 4,P<0.05)。并发组与未并发组的血脂指标差异无统计学意义(P>0.05)。结论凝血四项和血脂检测结果显示异常提示患者有出现糖尿病并发症的风险,对于糖尿病患者的诊断和预防有重要意义。
Objective To explore the clinical role of four blood coagulation and blood lipid tests in the examination of diabetic patients. Methods Sixty-seven diabetic patients admitted to our hospital from November 2016 to October 2017 were taken as the experimental group. The experimental group was divided into the complication group(33 cases) and the non-concurrent group(34 cases) according to the patient’s complications. Sixty-six healthy subjects who came to our hospital for physical examination were selected as the control group. The two groups were tested for blood coagulation and blood lipids, and the results were compared. Results There were statistically significant differences between the experimental group and the control group in the coagulation tests(PT, APTT, FIB, TT)(t=5.642 4, 8.087 4, 16.000 6,32.789 0, P<0.05). In the experimental group, the average PT content was(10.63±0.62) s, average APTT content was(28.70±5.21)s, average FIB content was(4.63±0.78)g/L, and average TT content was(13.39±0.57)s. Patients in the experimental group showed a high tendency to coagulate. There was no statistically significant difference in PT, TT and APTT between the patients with complications and the patients without complication(P>0.05). The FIB level in the complication group was significantly higher than that in the non-complication group(t=9.729 6, P=0.000 0). The average TC content of the experimental group was(5.41±1.31) mmol/L, the average TG content was(3.20±1.43) mmol/L, the average HDL-C content was(1.18±0.51) mmol/L, and the average LDL-C content was(3.15±1.39) mmol/L. There was statistically significant difference between the experimental group and the control group in blood lipid test(TC, TG,HDL-C, LDL-C)(t =3.846 9, 6.964 2, 6.389 7, 4.706 4, P <0.05). There was no statistically significant difference in blood lipids between the complication and non-complication groups(P>0.05). Conclusion The abnormality of four blood coagulation and blood lipid test results suggest that patients have the risk of diabetes complications, which is of great significance for the diagnosis and prevention for diabetic patients.
作者
朱宁
朱涛
ZHU Ning;ZHU Tao(Department of Clinical Laboratory, Integrated Traditional Chinese and Western Medicine Hospital of Nan'an District,Chongqing,400061 China;Department of Clinical Laboratory, Maternal and Child Health Family Planning Service Center of Nan'an District,Chongqing,400060 China)
出处
《系统医学》
2019年第15期31-33,共3页
Systems Medicine
关键词
糖尿病
凝血四项
血脂检验
Diabetes
Four blood coagulation tests
Blood lipid test
