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孟鲁司特钠联合沙美特罗替卡松粉吸入剂治疗小儿哮喘的临床效果分析 被引量:2

Clinical Effect Analysis of Montelukast Sodium Combined with Salmeterol and Fluticasone Powder Inhalation in Children with Asthma
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摘要 目的分析哮喘患儿接受孟鲁司特钠、沙美特罗替卡松粉吸入剂联合治疗的应用价值。方法该次选择2017年11月—2019年2月该院收治哮喘患儿120例为研究对象,根据入院先后顺序分为观察组与对照组,对照组患儿单纯以孟鲁司特钠治疗,观察组患儿在此基础上联用沙美特罗替卡松粉吸入剂治疗,比较临床总有效率,统计并分析各组患儿治疗后症状改善时间,统计并对比治疗前后两组患儿肺功能指标。结果观察组临床治疗总有效率明显优于对照组(P<0.05),且观察组患儿停止咳嗽时间(4.93±1.02)d、喘息停止时间(6.21±0.55)d、肺啰音消失时间(5.74±0.48)d均明显短于对照组(t=11.04、10.38、12.28,P<0.05)。两组患儿未接受治疗前肺功能各项指标差异无统计学意义(P>0.05),经治疗后,观察组患儿FEV1(1.62±0.23)L、PEF(4.33±0.12)L/s均明显高于对照组(t=8.49、9.35,P<0.05)。结论哮喘患儿采取孟鲁司特钠、沙美特罗替卡松粉吸入剂联合治疗效果更佳,可改善临床症状与患儿肺功能,值得推广应用。 Objective To analyze the value of combined treatment with montelukast sodium and salmeterol and ticatica powder inhalation in children with asthma. Methods From November 2017 to February 2019, 120 children with asthma were enrolled in this hospital. The patients were divided into observation group and control group according to the order of admission. The control group was treated with montelukast sodium alone. On the basis of this, the children in the observation group were treated with salmeterol and fluticasone powder inhalation. The total effective rate was compared. The time of symptom improvement after treatment was analyzed and analyzed. The lungs functional indicators of the two groups before and after treatment were compared and compared. Results The total effective rate of clinical treatment in the observation group was significantly better than that in the control group (P<0.05), and the cough time (4.93±1.02) d, wheezing stop time (6.21±0.55) d, and the disappearance time of the lung snoring were observed in the observation group (5.74±0.48)d were significantly shorter than the control group (t=11.04, 10.38, 12.28, P<0.05). There were no statistically significant differences in lung function parameters between the two groups before treatment(P>0.05). After treatment, the FEV1 (1.62±0.23) L and PEF (4.33±0.12) L/s were significantly higher in the observation group than in the control group (t=8.49, 9.35, P<0.05). Conclusion The combination of montelukast sodium and salmeterol ticatica powder inhalation is better in children with asthma, which can improve clinical symptoms and lung function in children. It is worthy of popularization and application.
作者 朱艳丽 ZHU Yan-li(Department of Pediatrics,Funing People's Hospital,Yancheng,Jiangsu Province,224400 China)
出处 《世界复合医学》 2019年第8期190-192,共3页 World Journal of Complex Medicine
关键词 孟鲁司特钠 沙美特罗替卡松 小儿哮喘 临床效果 Montelukast sodium Salmeterol rotticasone Asthma in children Clinical effect
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