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Reg Ⅳ在恶性肿瘤中的研究进展 被引量:4

Research progress in the role of Reg Ⅳ in malignant tumor
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摘要 再生因子4(Reg Ⅳ)是再生基因家族新发现的一员,主要在近端胃肠道表达,且异常表达于炎症损伤及肿瘤组织中,参与肿瘤的发生发展,诱导细胞的增殖、侵袭、转移及抗凋亡等。目前关于Reg Ⅳ的研究主要集中在消化系统,如胃癌、结直肠癌和胰腺癌等,在其他肿瘤中的研究报道相对较少。本文就Reg Ⅳ在多系统恶性肿瘤中的表达情况、对肿瘤恶性生物学行为的影响及潜在作用机制进行文献回顾,为临床肿瘤的早期预防、诊断和治疗寻找新的靶分子。
作者 宋姗姗 聂艳红 王红霞 陈昊 SONG Shan-shan;NIE Yan-hong;WANG Hong-xia
出处 《诊断病理学杂志》 2019年第7期460-463,465,共4页 Chinese Journal of Diagnostic Pathology
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