摘要
目的:比较腹腔镜根治性膀胱切除术(LRC)与开放性根治性膀胱切除术(ORC)治疗肌层浸润性膀胱癌(MIBC)的围手术期临床效果。方法:52例MIBC患者分为LRC组及ORC组,分别接受LRC和ORC治疗,观察手术时间、术中出血量、输血患者数量、术中输液量、血气分析、尿流改道类型、病例分期、术后肛门排气时间、恢复进食时间、住院时间,检测手术前后红细胞压积与肌酐水平,观察并发症发生情况。结果:LRC组接受输血的患者人数、术中总液体入量显著少于ORC组(P<0.05),术后肛门排气时间和恢复进食时间及住院时间显著短于ORC组(P<0.05),术后并发症发生率显著低于ORC组(P<0.05);两组术中血气分析结果均在正常范围之内,两组MIBC患者术前、术后及出院前红细胞压积与肌酐比较,差异无统计学意义(P>0.05),两组MIBC患者尿流改道类型和术后病理分期比较,差异无统计学意义(P>0.05)。结论:LRC治疗MIBC较ORC具有出血少、输血及输液量少、术后肠道功能恢复快、并发症发生率低、住院时间短等优点。
Objective:To compare the perioperative clinical effects of laparoscopic radical cystectomy(LRC)and open radical cystectomy(ORC)in the treatment of myometrial invasive bladder cancer(MIBC).Methods:52 patients with MIBC were divided into LRC group and ORC group,and were treated with LRC and ORC respectively to observe the operation time,the amount of intraoperative blood loss,the number of patients to be transfused,the amount of transfusion during the operation,the blood gas analysis,the type of urinary diversion,the case stage,the time after the operation of the anus,the time of recovery and the time of hospitalization.The level of Hematocrit and myocardiac was detected before and after operation,and the occurrence of complications was observed.Results:The number of patients receiving blood transfusion in LRC group was significantly lower than that in ORC group(P<0.05).The postoperative anal exsufflation time,recovery eating time and hospitalization time were significantly shorter than those in ORC group(P<0.05).The incidence of postoperative complications was significantly lower than that in ORC group(P<0.05).The results of intraoperative blood gas analysis in the two groups were within the normal range,and there was no significant difference in hematocrit and creatine between the two groups before,after and before discharge of MIBC(P>0.05).There was no significant difference in urinary flow diversion type and postoperative pathological stage between the two groups(P>0.05).Conclusion:Compared with ORC,LRC has the advantages of less bleeding,less blood transfusion and infusion,faster recovery of intestinal function after operation,low incidence of complications and short hospitalization time.
作者
王延东
王振兴
许美
徐元高
熊敏
舒芸
石华
WANG Yandong;WANG Zhenxin;XU Mei;XU Yuangao;XIONG Min;SHU Yun;SHI Hua(Department of Urinary Surgery,People's Hospital Affiliated to Guizhou Medical University,Guiyang 550002,Guizhou,China;Basic Medical College,Guizhou Medical University,Guiyang 550025,Guizhou,China;Operating Room,People's Hospital Affiliated to Guizhou Medical University,Guiyang 550002,Guizhou,China;People's Hospital Affiliated to Guizhou Medical University,Guiyang 550002,Guizhou,China)
出处
《贵州医科大学学报》
CAS
2019年第7期851-854,859,共5页
Journal of Guizhou Medical University
关键词
膀胱癌
肌层浸润
根治性膀胱切除术
腹腔镜
术后并发症
carcinoma of urinary bladde
muscle layer infiltration
radical cystectomy
peritoneoscope
postoperative complications
