摘要
目的评价患者年龄、性别及尿流改道方式对根治性膀胱切除术后并发症的影响。方法回顾性分析2000年3月至2011年6月中山大学肿瘤防治中心治疗的374例接受根治性膀胱全切并尿流改道术的膀胱癌患者的一般资料、手术类型和术后并发症，运用χ2检验和Logistic回归分析患者年龄、性别及尿流改道方式与术后并发症的关系。结果38．8％（145／374）的患者接受改良回肠导管术，47．9％（179／374）的患者接受改良回肠原位新膀胱术，13．4％（50／374）的患者接受乙状结肠原位新膀胱术。术后并发症发生率为37．4％（140／374），近期并发症（≤90d）发生率为21．4％（80／374），远期并发症（〉90d）为16．3％（61／374）。Logistic回归分析表明年龄（P=0．15）和性别（P=0．16）与术后并发症无关，尿流改道方式影响并发症发生（OR=0．26，95％CI：0．16～0．43）。结诊尿流曲谱肯式县影响根治一件陪胱切除术后并发症的重要因素。
Objective To explore the association of age, gender and urinary diversion category with postoperative complications of radical cystectomy. Methods A total of 374 patients with bladder cancer undergoing modified radical cystectomy and urinary diversion between March 2000 and June 2011 were retrospectively reviewed. Their demographic, perioperative and complication data were recorded. And multivariable Logistic regression was used to investigate the predictors of perioperative complications. Results Among them, 38.8% （ 145/374 ） received ileal conduit, 47. 9% （ 179/374 ） orthotopic ileal neobladder and 13.4% （50/374） orthotopic colonic neobladder. The overall perioperative complication rate was 37.4% （140/374）. And 21.4% （80/374）experienced at least one complication within Day 90 postoperation while 16. 3% （61/374）had the long-term complications（ 〉 Day 90）. There was no significant association between patients age （ P = 0. 15 ） and perioperative complications or between gender （ P = 0. 16） and complication. Urinary diversion （ OR = 0. 26,95 % CI： 0. 16 - 0.43 ） was the only variable significantly associated with the perioperative urinary complications. Conclusion The categories of urinary diversion may be used as a single oredietor for comolications after radical cystectomy.
出处
《中华医学杂志》
CAS
CSCD
北大核心
2012年第32期2280-2282,共3页
National Medical Journal of China
关键词
膀胱肿瘤
膀胱切除术
手术后并发症
尿流改道术
Bladder neoplasms
Cystectomy
Postoperative complications
Urinary diversion
