摘要
认知障碍指与学习、记忆、语言、思维、情感等有关的大脑高级智能加工过程出现异常,导致注意障碍、记忆障碍、执行障碍等,已经成为严重的社会公共健康问题,但目前仍缺乏安全有效疗法。转化生长因子β1(tansforming growth factor beta 1,TGF-β1)是TGF-β家族中的最重要成员之一,可通过多种途径改善认知功能,为认知障碍的治疗提供新的策略。作者对TGF-β1在认知障碍中的作用研究进展进行综述。
Cognitive dysfunction refers to abnormalities in the brain’s advanced intelligent processing processes related to learning,memory,language,thinking and emotion,which leaded to attention,memory and executive dysfunction. It has become a serious social public health problem,but it still lacks of safe and effective therapy. Tansforming growth factor beta 1( TGF-β1) is one of the most important members of the TGF-β family,which can improve cognitive function through various ways and provide new strategies for the treatment of cognitive dysfunction. This paper reviews the research progress of the role of TGF-β1 in cognitive dysfunction.
作者
薛志远
徐平
XUE Zhiyuan;XU Ping(Department of Neurology,Affiliated Hospital of Zunyi Medical University,Zunyi Guizhou 563000,China)
出处
《转化医学杂志》
2019年第3期186-188,共3页
Translational Medicine Journal
关键词
认知障碍
转化生长因子-Β1
神经递质
肠道菌群
脂联素
Cognitive dysfunction
Tansforming growth factor beta 1(TGF-β1)
Neurotransmitters
Gut microbial
Adiponectin
