摘要
缺血缺氧性脑损伤(hypoxic-ischemic brain damage, HIBD)是由于多种因素引起局部脑组织血液循环障碍而导致脑组织的软化、坏死。神经元对缺血缺氧环境极为敏感,在脑损伤后短时间内,可引起脑内神经元和突触的损伤,严重影响中枢神经系统信息的传递,目前,对突触的损伤及修复的研究也有了一定的进展。本文就对缺血缺氧性脑突触损伤的机制和修复作一综述。
Hypoxic-ischemic brain damage (HIBD) is caused by a variety of factors resulting in regional cerebral blood circulation disorders and consequent brain tissue softening and necrosis. Neurons are extremely sensitive to ischemic and anoxic conditions, which can cause neuronal and synaptic damage in the brain within a short period of time after brain injury, and seriously affect the transmission of information in the central nervous system. Some progress has been made in the study of synaptic damage and its regeneration. This article reviews the mechanisms underlying ischemic hypoxic brain synaptic injury and its regeneration.
作者
黄媛媛
汪萌芽
HUANG Yuan-yuan;WANG Meng-ya(Wannan Medical College Cell Electrophysiology Laboratory, Anhui Wuhu 241002, China)
出处
《科技视界》
2019年第9期211-213,共3页
Science & Technology Vision
关键词
突触
损伤
修复
Synapse
Injury
Repair
