摘要
探讨血清PGⅠ、PGⅡ联合AFP检测在胃癌临床诊断中的应用价值.方法:选取2015年1月?2017车2月于我院就诊胃癌患者52例作为观察组,并选取同期于我院体检的健康人52例作为对照组,对比两组血清PGⅠ、PGⅡ、AFP水平.结果:观察组血清PGⅠ水平、PGⅠ/PGⅡ比值显著低于对照组,AFP水平显著高于对照组(P<0.05);胃癌患者治疗后的PGⅠ、PGⅡ、AFP水平显著低于治疗前(P<0.05)。复发转移患者的PGⅠ、PGⅡ、AFP水平显著高于未复发转移患者(P<0.05).PGⅠ . PGⅡ联合AFP检测的准确度、敏感度、特异度显著高于单一指标(P<0.05).结论:血清PGI、PGⅡ联合AFP检测可以有效提高胃癌的检测准确性,可用于早期胃癌筛查及预后评估.
Objective: To explore the clinical value of serum PGⅠ, PGⅡ combined with AFP in the clinical diagnosis of gastric cancer. Methods: 52 patients with gastric cancer from January 2015 to February 2017 were selected as the observation group, and 52 healthy people were selected as the control group. Serum PGⅠ, PG Ⅱ and AFP levels were compared between the two groups. Results: The serum PGⅠ level and PGⅠ/ PGⅡ ratio in the observation group were significantly lower than those in the control group, and the AFP level was significantly higher than that in the control group (P<0.05). The levels of PGⅠ, PGⅡ and AFP in patients with recurrence and metastasis were significantly higher than those in patients without recurrence or metastasis (P<0.05). The accuracy, sensitivity and specificity of PGⅠ, PG Ⅱcombined with AFP were significantly higher than those of single index (P<0.05). Conclusion: Serum PG Ⅰ, PG Ⅱ combined with AFP can effectively improve the accuracy of gastric cancer detection, and can be used for early gastric cancer screening and prognosis evaluation.
作者
谭锦平
叶锦希
钟锦开
陈悦晶
陈旭森
TAN Jin-ping;YE Jin-xi;ZHONG Jin-kai(Dongguan Hongmei Hospital, Guangdong Dongguan 523160)
出处
《医学检验与临床》
2019年第3期5-8,共4页
Medical Laboratory Science and Clinics
基金
东莞市科技计划医疗卫生类科研一般项目(项目编号:201610515000644).
