摘要
目的了解上海市嘉定区儿童感染性腹泻中病原菌分布情况。方法依托上海市儿童腹泻病监测工作,从2015年5月—2018年4月采集某哨点医院感染性腹泻的儿童粪便标本333例,开展肠道病原菌检测。结果 74例(22.2%)检出病原菌,包括肠致泻性大肠杆菌52例(15.6%),其中非典型EPEC32株、EAEC17株、STEC2株、ETEC2株,1例EAEC和ETEC混合感染,1例STEC O157:H7;沙门菌18例(5.4%);空肠弯曲菌6例(1.8%);副溶血性弧菌和小肠结肠炎耶尔森菌各1例(0.3%);未检出志贺菌;肠致泻性大肠杆菌检出率夏秋季与冬春季相比差异有统计学意义(χ2=28.774,P <0.05);肠致泻性大肠杆菌和沙门菌在各年龄段间和男女间相比均差异无统计学意义(χ2=5.313、4.925,P> 0.05;χ2=2.941、0.050,P> 0.05)。结论引起儿童感染性腹泻的病原菌主要为肠致泻性大肠杆菌、沙门菌和空肠弯曲菌;肠致泻性大肠杆菌在夏秋季易感,以EPEC和EAEC为主;沙门菌以鼠伤寒、肠炎血清型为主。
Objective To understand the distribution of pathogenic bacteria for Children's infectious diarrhea in Jiading District of.Methods Relying on Shanghai monitoring for children's diarrhea,333 fecal samples of children with infectious diarrhea from May 2015 to April 2018 had been collected from a sentinel hospital for carrying out enteric pathogenic bacteria detection.Results Pathogenic bacteria were detected in 74 cases (22.2%),including 52 cases (15.6%) of diarrheogenic Escherichia coli,there were 32 strains of EPEC,17 strains of EAEC,2 strains of STEC and 2 strains of ETEC,1 case of mixed infection of EAEC and ETEC,1 case of STEC O157 : H7;18 cases (5.4%) of salmonella;campylobacter jejuni 6 cases (1.8%);each 1 case of vibrio parahaemolyticus and Yersinia enterocolitica (0.3%) was detected,shigella was not detected.The detection rate of diarrheogenic Escherichia coli in summer and autumn was significantly different from that in winter and spring (χ^2=28.774,P < 0.05);There was no significant difference in the detection rates of diarrheogenic Escherichia coli and Salmonella between different age groups (χ^2=5.313、4.925,P > 0.05) and between boys and girls (χ^2=2.941、0.050,P > 0.05).Conclusion The major pathogenic bacteria causing Children's infectious diarrhea are diarrheogenic Escherichia coli,salmonella and campylobacter jejuni.The diarrheogenic Escherichia coli is mainly EPEC and EAEC,and is susceptible to infection in summer and autumn;salmonella is mainly S.typhimurium and S.enteritidis.
作者
余玮
孙攀
彭谦
宣栋樑
YU Wei;SUN Pan;PENG Qian;XUAN Dongliang(Department ofMicrobiological Detection,Jiading District Center for Disease Control andPrevention,Shanghai 201899,China;Office of the Deputy Director,Jiading District Center for Disease Control andPrevention,Shanghai 201899,China;Department of Quality Management,Jiading District Center for Disease Control andPrevention,Shanghai 201899,China)
出处
《中国卫生标准管理》
2019年第7期82-85,共4页
China Health Standard Management
关键词
感染性腹泻
肠致泻性大肠杆菌
产志贺毒素大肠杆菌
毒力基因
沙门菌
儿童
infectious diarrhea
diarrheagenic Escherichia coli
shiga toxin-producing Escherichia coli
toxicity gene
salmonella
children
