摘要
目的:分析氨溴索联合布地奈德雾化吸入治疗新生儿肺炎的临床疗效。方法:选取我院2018年1月至2018年6月收治的74例新生儿肺炎,按照治疗方法的不同平均分为对照组、观察组,对照组采用氨溴索进行治疗,观察组使用氨溴索与布地奈德联合雾化吸入治疗,对比两组患者治疗后潮气呼吸肺功能指标、各项临床症状消失时间及住院时间。结果:治疗后,观察组患儿各项潮气呼吸肺功能指标(RR、VT、TPEF/TE、VPEF/VE、PEF)改善情况均优于对照组,且各组比较均P<0.05,有统计学差异;观察组患儿肺部啰音、口唇紫绀、气促等临床症状消失时间以及住院时间均短于对照组,P<0.05,存在统计学意义。结论:对新生儿肺炎采用氨溴索联合布地奈德雾化吸入治疗可明显改善患儿各项潮气呼吸肺功能指标,加快各项临床症状的消失,缩短住院时间,具有良好的临床效果。
Objective: To analyze the clinical effect of ambroxol combined with budesonide atomization inhalation in the treatment of neonatal pneumonia. Methods: 74 cases of neonatal pneumonia admitted in our hospital from January 2018 to June 2018 were divided into control group, observation group and control group. The observation group was treated with combined atomization inhalation of ambroxol and budesonide. The indexes of respiratory and pulmonary function, the time of disappearance of clinical symptoms and the time of hospitalization were compared between the two groups. Results: After treatment, the indexes of tidal breathing and lung function (RR,VT,TPEF/TE,V) were observed in the observation group. The improvement of PEF/VE, PEF was better than that of control group (P<0.05). The clinical symptoms such as lung rale, cyanosis and shortness of breath in the observation group were shorter than those in the control group (P<0.05). Conclusion: The treatment of neonate pneumonia with ambroxol combined with budesonide atomization inhalation can obviously improve the pulmonary function index of tidal breathing, accelerate the disappearance of clinical symptoms, shorten the hospitalization time, and have good clinical effect.
作者
陈秋萍
覃广平
罗勤
CHEN Qiu-ping;QIN Guang-ping;LUO Qin(Pingxiang People's Hospital, Pingxiang Jiangxi 337000, China)
出处
《药品评价》
CAS
2019年第7期62-64,共3页
Drug Evaluation
关键词
氨溴索
布地奈德
雾化吸入
新生儿肺炎
临床分析
Ambroxol
Budesonide
Atomization Inhalation
Neonatal Pneumonia
Clinical Analysis
