摘要
目的探讨巴曲酶联合神经节苷脂治疗急性脑梗死的临床疗效。方法选取2017年1月～2018年6月于我院就诊的急性脑梗死患者100例作为研究对象,两组患者均予脱水、降压、降脂、降糖、抗凝及抗自由基等常规治疗,观察组同时联合巴曲酶和神经节苷脂治疗,两组均连续治疗14 d,治疗后对比分析两组的临床疗效、治疗前后NIHSS评分的变化情况。结果观察组与对照组的基本治愈率分别为40.0%、38.0%,两组比较,差异不显著(P>0.05)。观察组与对照组患者治疗后的总有效率分别为96.0%、76.0%,两组疗效对比,差异存在显著性(P<0.05)。观察组患者治疗1周后的NIHSS评分为(14.82±5.28)分、治疗2周后的NIHSS评分为(7.97±1.39)分,均显著低于治疗前,差异具有统计学意义(P<0.05)。结论巴曲酶联合神经节苷脂治疗急性脑梗死可以显著提高临床疗效,从而发挥保护脑细胞、促进神经功能恢复的作用。
Objective To explore the clinical efficacy of batroxobin combined with ganglioside in the treatment of acute cerebral infarction. Methods A total of 100 patients with acute cerebral infarction who were treated in our hospital from January 2017 to June 2018 were selected as subjects. Both groups were treated with conventional treatments such as dehydration, hypotension, lipid lowering, hypoglycemic, anticoagulant and anti-free radicals. The observation group was combined with batroxobin and ganglioside treatment. The two groups were treated continuously for 14 days. After treatment, the clinical efficacy and the changes of NIHSS scores before and after treatment were compared. Results The basic cure rates of the observation group and the control group were 40.0% and 38.0%, respectively, and the difference between the two groups was not significant (P>0.05). The total effective rate of the observation group and the control group after treatment was 96.0% and 76.0%, respectively, showing significant difference between the two groups(P<0.05). The NIHSS score of the observation group was (14.82±5.28) points after 1 week of treatment, and (7.97±1.39) points after 2 weeks of treatment, which were significantly lower than those before treatment, and the differences were statistically significant(P<0.05). Conclusion Batroxobin combined with ganglioside in the treatment of acute cerebral infarction can significantly improve the clinical efficacy, thereby playing a role in protecting brain cells and promoting the recovery of nerve function.
作者
赵晶
ZHAO Jing(Department of Neurology, the 960th Hospital of the PLA, Zibo 255300, China)
出处
《中国现代医生》
2019年第8期46-48,共3页
China Modern Doctor
