摘要
目的:分析在慢性精神分裂症患者中实施病区内易操作易实施康复训练配合奥氮平口服对其社会和认知功能的影响。方法:选取2017年3月-2018年4月本院收治的100例精神分裂症患者。按照随机数字表法将其分为对照组和研究组,各50例。对照组予以奥氮平口服治疗,研究组在对照组基础上配合病区内易操作易实施康复训练。比较两组治疗前后的社会功能(PANSS、SDSS、ADL评分)和认知功能(IQ、WCST评分),以及治疗效果。结果:治疗后,两组PANSS、SDSS评分均低于治疗前,ADL评分均高于治疗前,且研究组均优于对照组,差异均有统计学意义(P<0.05);治疗后,两组IQ值均高于治疗前,WCST评分均低于治疗前,且研究组IQ值高于对照组,WCST评分低于对照组,差异均有统计学意义(P<0.05);研究组总有效率为80.00%,高于对照组的62.00%(P<0.05)。结论:在慢性精神分裂症患者应用病区内易操作易实施康复训练配合奥氮平口服,更利于改善患者的社会功能和认知功能,并可提高治疗效果。
Objective:To analyze the effects of easy-to-operate and easy-to-implement rehabilitation training in the ward combined with Olanzapine oral administration on the social and cognitive functions in patients with chronic schizophrenia.Method:A total of 100 schizophrenic patients admitted to our hospital from March 2017 to April 2018 were selected.According to the random number table method,they were divided into control group and study group,50 cases in each group.The observation group was given Olanzapine oral administration,while the control group was given easy-to-operate and easy-to-implement rehabilitation training in the ward on the basis of control group.The social function(PANSS,SDSS,ADL score)and cognitive function(IQ,WCST score)before and after treatment,and therapeutic effect of two groups were compared.Result:After treatment,the scores of PANSS and SDSS in two groups were lower than those of before treatment,ADL scores were higher than those of before treatment,and study group were better than those of control group,the differences were statistically significant(P<0.05).After treatment,the IQ values of two groups were higher than those of before treatment,WCST scores were lower than those of before treatment,and IQ values of study group was higher than that of control group,WCST score was lower than that of control group,the differences were statistically significant(P<0.05).The total effective rate was 80.00%in study group,which was higher than 62.00%of control group(P<0.05).Conclusion:The application of easy-to-operate and easy-to-implement rehabilitation training in the ward combined with Olanzapine oral in patients with chronic schizophrenia is more conducive to improving patients'social function,cognitive function and improve the therapeutic effect.
作者
李福金
王飞
李红丽
叶百维
LI Fujin;WANG Fei;LI Hongli(Huizhou Second People’s Hospital,Huizhou 516003,China)
出处
《中国医学创新》
CAS
2019年第9期153-156,共4页
Medical Innovation of China
基金
惠州市科学技术局课题(180515191743369)
关键词
精神分裂症
康复训练
奥氮平
社会功能
认知功能
Schizophrenia
Rehabilitation training
Olanzapine
Social function
Cognitive function