摘要
目的近年来有关恶性肿瘤死亡年龄变化趋势Joinpoint回归分析的研究报道较少。本研究分析2011—2015年丰台区恶性肿瘤死亡年龄变化趋势,为制定不同年龄人群恶性肿瘤防治策略提供依据。方法利用2011—2015年北京市丰台区死亡资料数据库及常住人口数,计算死亡率等指标。应用Joinpoint回归对不同年份、不同性别、主要癌种的恶性肿瘤年龄别死亡率进行比较。结果 50～69岁恶性肿瘤总死亡率在5年间从285.51/10万上升到460.80/10万。肺癌、结直肠癌、肝癌、胃癌、胰腺癌是死亡人数较多的癌种。男性恶性肿瘤死亡率平均每岁上升6.78%(t=0.293,P=0.771),女性平均每岁上升6.56%(t=14.483,P<0.001),男女年龄别死亡率转折点不同。男性肺癌、肝癌和胃癌死亡率分别在30～69岁、<75岁和≥55岁死亡率上升较明显,女性结直肠癌、胃癌和胰腺癌分别在55～69岁、≥25和≥75岁死亡率上升较明显。结论在癌症防治工作中,将≥55岁的女性结直肠癌、男性肝癌和全人群的胃癌,及≥30岁的男性肺癌和≥75岁的女性胰腺作为重点干预的高死亡风险年龄别人群,有助于从整体上降低居民癌症年龄别死亡率。
OBJECTIVE In recent years,malignant tumors have become the first death cause in China,and there are few studies on the trend of malignant tumors death age by Joinpoint regression analysis.The objective of this study was to understand the death age trend of malignant tumors in Fengtai District from 2011 to 2015,and to provide evidence for formulating strategies for malignant tumors prevention and treatment in different age groups.METHODS Using mortality database and resident population in Fengtai District, Beijing from 2011 to 2015, to calculated mortality and other indicators.Joinpoint regression was Uvsed to compare the age mortality of malignant tumors of different years,gender and major cancer species.RESULTS At the age of 50-69, the total mortality rate of malignant tumors increased from 285.51 10 million to 460.80/10 million in 5 years.Lung cancer,colorectal cancerЛ??ег cancer,gastric cancer and pancreatic cancer are the most common cancers.The average mortality of male malignant tumors was increased by 6.78%(t=0.293,F =0.771), which of the female was increased 6.56 %(t=14.483,P<0.001) for each year?and the turning point of male and female age mortality was different.The mortality of male lung cancer,liver cancer and gastric cancer were increased significantly at the age of 30-69,<C75 and ≥55.The mortality of female colorectal cancer,gastric cancer and pancreatic cancer were increased significantly at the age of 55-69,≥25 and ≥75.CONCLUSION In the cancer prevention and control,the female colorectal cancer,male liver cancer and whole population, gastric cancer after 55 years old,and male lung cancer after 30 years old and female pancreatic cancer after 75 years old as the key intervention age groups.
作者
马晓曼
谢俊卿
王琳
罗艳侠
安吉
李洁
MA Xiao-man;XIE Jun-qing;WANG Lin;LUOYan-xia;AN Ji;LI Jie(Department of Nutrition and Food Hygiene,Fengtai Centers for Diseases Control and Prevention,Beijing 100071,P.R.China;Department of Epidemiology and Health Statistics,School of Public Health,Capital Medical University,Beijing 100069,P.R.China)
出处
《中华肿瘤防治杂志》
CAS
北大核心
2019年第3期137-141,共5页
Chinese Journal of Cancer Prevention and Treatment
基金
国家"十三五"科技支撑计划(2016YFC1302804)
关键词
恶性肿瘤
死亡率
年龄
变化
防治
malignant tumor
mortality
age
change
prevention and treatment
