摘要
随着恶性肿瘤诊疗技术的不断进步,青少年恶性肿瘤幸存者的人数也日益增加。目前已证实,烷化剂类药物和盆腔放疗可影响青春期正常发育,并可能损害患者的生育能力。为保留青少年恶性肿瘤患者的生育能力,在治疗前可考虑采用卵母细胞冷冻保存、精子冷冻保存、卵巢组织冷冻保存和睾丸组织冷冻保存等方法。
The number of adolescent survivors with malignant tumor is growing rapidly as the progression in diagnosis and treatment. However, many anti-tumor therapeutic methods, especially chemotherapy with alkylating agents and pelvic radiation therapy have been demonstrated to injure normal pubertal development and may lead to permanent infertility, significantly impacting quality of life. Thus, fertility preservation, such as oocyte cryopreservation, sperm cryopreservation, ovarian tissue cryopreservation and testicular tissue cryopreservation, prior to cancer therapy, must be considered to meet the future reproductive demands of adolescent survivors with malignant tumor.
出处
《肿瘤》
CAS
CSCD
北大核心
2013年第10期935-938,共4页
Tumor
关键词
肿瘤
青少年
不育
保留生育功能
Neoplasms
Adolescent
Infertility
Fertility preservation
