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左氧氟沙星与头孢哌酮舒巴坦联合治疗老年肺炎的疗效观察 被引量:8

Observation on Efficacy of Levofloxacin and Cefoperazone Sulbactam in the Treatment of Senile Pneumonia
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摘要 目的观察左氧氟沙星与头孢哌酮舒巴坦联合治疗老年肺炎的疗效。方法选取本院2016年3月—2018年2月收治的老年肺炎患者98例作为研究对象。将患者随机分为两组,每组各49例患者。对照组给予头孢哌酮钠舒巴坦治疗,观察组联合给予左氧氟沙星治疗,观察两组患者治疗后的肺功能以及预后,采用SPSS 20.0软件对两组患者的肺功能指标以及预后指标进行评价及对比。结果治疗后,观察组患者的FEV_1为(2.01±0.05)L、FVC(3.00±0.75)L、PEF(8.15±0.14)L/s、症状消失时间(3.89±0.87)d、治疗有效率为97.96%、住院时间(4.87±1.20)d。治疗后,对照组患者的FEV_1(1.46±0.10)L、FVC(2.28±0.09)L、PEF(4.54±0.01)L/s、症状消失时间(6.44±1.26)d、治疗有效率85.71%、住院时间(8.79±1.36)d。两组各项数据对比,差异具有统计学意义(P <0.05)。结论采用左氧氟沙星与头孢哌酮舒巴坦联合治疗老年肺炎,可改善患者的肺功能,促使症状消失,疗效显著。 Objective To observe the efficacy of levofloxacin combined with cefoperazone sulbactam in the treatment of senile pneumonia.Methods 98 elderly patients with pneumonia admitted to our hospital from March 2016 to February 2018 were selected as the subjects of study.The patients were randomly divided into two groups,49 patients in each group.The control group was treated with cefoperazone sodium and sulbactam.The observation group was treated with levofloxacin.The lung function and prognosis of the two groups were observed after treatment.SPSS 20.0 software was used to evaluate and compare the lung function index and prognostic index of the two groups.Results In the observation group,the FEV1(2.01±0.05)L,FVC(3.00±0.75)L,PEF was(8.15±0.14)L/s,the symptom disappeared time was(3.89±0.87)d,the effective rate was 97.96%and the hospitalization time was(4.87±1.20)days.In the control group,FEV1(1.46±0.10)L,FVC(2.28±0.09)L,PEF(4.54±0.01)L/s,the symptom disappearance time was(6.44±1.26)d,the effective rate was 85.71%and the hospitalization time(8.79±1.36)d respectively.There was significant difference between the two groups(P<0.05).Conclusion The combination of levofloxacin and cefoperazone sulbactam in the treatment of senile pneumonia can improve the pulmonary function of patients,promote the disappearance of symptoms,and have a significant effect.
作者 李洪俊 LI Hongjun(Geriatrics Department,Leling City People's Hospital,Heze Shandong 253600,China)
出处 《中国卫生标准管理》 2019年第4期81-83,共3页 China Health Standard Management
关键词 左氧氟沙星 头孢哌酮舒巴坦 肺炎 肺功能 有效率 不良反应 levofloxacin cefoperazone sulbactam pneumonia lung function efficiency adverse reactions
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