摘要
目的探讨血清降钙素原(PCT)、C-反应蛋白(CRP)的检测在老年患者肺炎抗菌治疗中的作用。方法选取该院呼吸内科2015年5月至2016年3月收治的老年肺炎患者91例,分为观察组和对照组,对照组患者根据临床医生的临床判断给予抗菌药物的治疗,观察组患者则根据机体内PCT和CRP的水平给予适当、适量的抗菌药物治疗。比较两组患者血清相关指标情况、住院治疗情况,以及两者相应指标的相关性情况。结果观察组患者血清PCT、CRP、WBC明显低于对照组,且差异均有统计学意义(t=6.948、5.721、2.901,P<0.05);观察组患者抗菌药物使用时间明显短于对照组,且差异均有统计学意义(P<0.05);观察组患者血清PCT、CRP、WBC与抗菌药物使用时间长短均呈正相关(r=0.720、0.684、0.430,P<0.05)。结论血清PCT、CRP的检测对老年肺炎抗菌治疗具有良好的指导作用,值得在临床中推广应用。
Objective To investigate the role of serum calcitonin（PCT）and C-reactive protein（CRP）in the antibacterial treatment of senile pneumonia.Methods A total of 91 cases of respiratory medicine in our hospital from May 2015-2016 year in March from pneumonia in the elderly patients,were randomly divided into observation group and control group,control group patients according to the clinical judgment of the clinicians given antibiotic treatment,patients in the observation group according to the body PCT and CRP level of antibiotic treatment,the appropriate amount.Compared the two groups of patients with serum related indicators,hospital treatment,as well as the correlation between the two indicators.Results The observation group patients serum PCT（t=6.948,P〈0.001）,CRP（t=5.721,P〈0.001）,WBC（t=2.901,P=0.005）was significantly lower than the control group,and the differences were statistically significant（P〈0.05）;patients in the observation group use of antibiotics（t=3.667,P〈0.001）was significantly shorter than the control group,and the differences were statistically significant（P〈0.05）;serum PCT（r=0.720,P〈0.001）,CRP（r=0.684,P〈0.001）,WBC（r=0.430,P=0.004）and duration of antibiotic use duration were significantly correlated,and the difference was statistically significant（P〈0.05）.Conclusion The detection of serum PCT and CRP plays an important role in the treatment of pneumonia in elderly patients.It is worth popularizing in clinical practice.
作者
宋荟琴
SONG Huiqin(Department of Clinical Laboratory,Center Hospital of Tongchuan Bureau of Mine Affairs,Tongchuan,Shaanxi 727000,China)
出处
《检验医学与临床》
CAS
2018年第18期2744-2746,共3页
Laboratory Medicine and Clinic
关键词
血清降钙素
血清C-反应蛋白
老年肺炎患者
效果分析
serum calcitonin
serum C-reactive protein
elderly patients with pneumonia
analysis of the effect
