摘要
目的探讨阿托伐他汀钙片治疗缺血性脑卒中颈动脉斑块的临床效果及其对复发率的影响。方法选择2016年3月至2017年3月本院收治的存在颈动脉斑块的首次发病的缺血性脑卒中患者120例,根据随机信封法将其分为观察组和对照组,各60例。对照组采用阿司匹林进行治疗,观察组给予阿司匹林+阿托伐他汀钙片治疗。比较两组患者的治疗效果。结果治疗后,两组TG、TC及LDL-C水平均显著降低,且观察组低于对照组(P<0.05);治疗后,观察组的颈动脉斑块面积及动脉狭窄率均显著优于对照组与治疗前(P<0.05);观察组缺血性脑卒中复发率低于对照组(P<0.05)。结论阿托伐他汀钙片治疗缺血性脑卒中效果显著,能够缩小颈动脉斑块面积,改善患者血脂水平,降低复发率,值得临床推广应用。
Objective To investigate the clinical effect of atorvastatin calcium tablets in the treatment of carotid plaque in ischemic stroke and its influence on recurrence rate.Methods A total of 120 cases of first-time ischemic stroke patients with carotid plaque admitted in our hospital from March 2016 to March 2017 were selected and divided into observation group and control group according to random envelope method,with 60 cases in each group.The control group was treated with aspirin,while the observation group was treated with aspirin+atorvastatin calcium tablets.The therapeutic effects of the two groups were compared.Results After treatment,the levels of TG,TC and LDL-C in the two groups significantly decreased,and those of the observation group were lower than the control group(P<0.05).After treatment,the carotid plaque area and arterial stenosis rate in the observation group were significantly better than those in the control group and before treatment(P<0.05).The recurrence rate of ischemic stroke in the observation group was lower than that in the control group(P<0.05).Conclusion Atorvastatin calcium tablets is effective in the treatment of ischemic stroke.It can decrease the area of carotid plaque,improve the levels of blood lipid and decrease the recurrence rate.It is worthy of clinical popularization and application.
作者
麻友兵
高英玲
杨桂春
王岩
MA You-bing;GAO Ying-ling;YANG Gui-chun;WANG Yan(Neurology Department, Hanzhong Railway Central Hospital, Hanzhong 723000, China)
出处
《临床医学研究与实践》
2019年第3期21-22,共2页
Clinical Research and Practice
