摘要
目的研究分析妊娠期糖尿病患者的空腹血糖水平的变化与不良妊娠结局之间的关系。方法从2017年3月～2018年3月在本院进行治疗的妊娠期糖尿病患者中随机抽取60例作为观察组研究对象,再抽取60例健康产妇作为对照组研究对象,利用葡萄糖氧化酶法检测患者的血清空腹血糖(FBG)、餐后2h血糖(PBG),再对两组患者的不良妊娠结局进行对比,观察分析两组妊娠期糖尿病患者血糖水平的变化与不良妊娠结局之间的关系。结果观察组患者的FBG、PBG水平显著高于对照组患者,且组间差异有统计学意义(P <0.05);观察组患者肝内胆汁淤积症、胎膜早破、早产、产后出血、胎儿窘迫等不良症状结局出现率显著低于对照组患者,且组间差异对比具有统计学意义(P <0.05);利用Spearman分析发现,患者的FBG、PBG水平的变化与肝内胆汁淤积症、胎儿窘迫、胎膜早破、新生儿高胆红素血症、新生儿肺炎等呈显著的正相关性(P <0.05)。结论妊娠期糖尿病孕妇的血糖水平与多种不良妊娠结局有密切相关,应当重视妊娠期糖尿病孕妇的血糖水平控制,改善妊娠结局。
Objective To study the relationship between changes in fasting blood glucose levels and adverse pregnancy outcomes in patients with gestational diabetes. Methods A total of 60 patients with gestational diabetes mellitus who were treated in our hospital from March 2017 to March 2018 were randomly selected as the observation group. 60 healthy women were selected as the control group and tested by glucose oxidase method. The patient’s serum fasting blood glucose(FBG), postprandial 2 h blood glucose(PBG), and then compare the adverse pregnancy outcomes of the two groups of patients, observed and analyzed the relationship between the changes in blood glucose levels and adverse pregnancy outcomes in the two groups of gestational diabetes patients. Results The levels of FBG and PBG in the observation group were significantly higher than those in the control group(P < 0.05). The patients in the observation group had intrahepatic cholestasis, premature rupture of membranes, premature delivery, postpartum hemorrhage, and fetus. The incidence of adverse symptoms such as distress was significantly lower than that of the control group(P < 0.05). Spearman analysis showed that the changes of FBG and PBG levels in patients with intrahepatic cholestasis fetus. There was a significant positive correlation between distress, premature rupture of membranes, neonatal hyperbilirubinemia, neonatal pneumonia(P < 0.05). Conclusions The blood glucose level of pregnant women with gestational diabetes is closely related to many adverse pregnancy outcomes. It is necessary to pay attention to the control of blood glucose levels in pregnant women with gestational diabetes and improve pregnancy outcomes.
作者
徐建玲
XU Jian-ling(Xinmi City Maternal and Child Health Hospital,Xinmi,Henan,452370,China)
出处
《临床研究》
2019年第1期32-33,共2页
Clinical Research
关键词
妊娠期糖尿病
血糖水平变化
不良妊娠结局
相关性
gestational diabetes
changes in blood glucose levels
adverse pregnancy outcomes
correlation
