摘要
目的目的探讨血清淀粉样蛋白A(SAA)在传染性单核细胞增多症(IM)患儿中的疾病诊断及病情转归的应用价值。方法2016年1月至2016年12月该院收治的86例IM患儿作为研究对象,另选48例正常儿童作为健康对照组。胶体金法检测两组SAA水平,同时常规检测C-反应蛋白(CRP)和白细胞(WBC)水平。采用t检验作为统计学方法。结果治疗前传染性单核细胞增多症(IM)患儿组SAA水平为107.65±69.81mg/mL,显著高于健康对照组(6.92±0.71mg/L,P<0.01);治疗前IM患儿CRP,WBC水平分别为(7.84±8.11mg/mL,13.00±8.33×109/L),也显著高于健康对照组(P<0.01),并且,治疗恢复后,SAA水平与治疗前比显著下降(7.27±1.92mg/L,P<0.01)。结论SAA作为一种快速、敏感的检测指标,对IM的临床诊断及病情转归有较高的应用价值,能为临床医生对IM的诊断及疗效监测提供帮助。
Objective To explore the clinical application value of serum amyloid A(SAA)in diagnosis and prognosis of infectious mononucleosis(IM).Methods The serum levels of SAA,C-reactive protein(CRP)and white blood cell(WBC)were detected in86children with IM who were admitted in Guangzhou Women and Children Medical Center from January2016to December2016.And48healthy children were enrolled as healthy control group.Results The levels of SAA in IM group before treatment and control group were107.65±69.81and6.92±0.71mg/L,respectively,which was statistically different(P<0.01);The CRP and WBC levels in IM group before treatment were7.84±8.11mg/mL,13.00±8.33×109/L respectively,which were significantly higher than the control group(P<0.01).Also,the levels of SAA in IM group aftertreatment(7.27±1.92mg/L)were significantly decreased compared to IM group before treatment(P<0.01).Conclusion SAA can provide useful auxiliary information for the diagnosis and prognosis of IM,which is worthy of extensive clinical application.
作者
姚淑雯
何艳明
容莉莉
周珍文
YAO Shuwen;HE Yanming;RONG Lili;ZHOU Zhenwen(Department of Clinical Laboratory,Guangzhou Women and Children Medical Center,Guangzhou,Guangdong 510120)
出处
《国际检验医学杂志》
CAS
2017年第A02期75-77,共3页
International Journal of Laboratory Medicine
