摘要
The effect of plant (rapeseed and grape seed) polyphenols on lipid metabolism of rat fed with high fat diet was studied. 30 rats were divided into 5 groups including group Z (basal diet), C (high fat diet without plant polyphenol), S (high fat diet with rapeseed polyphenols), R (high fat diet with grape seed polyphenols) and F (combined with rapeseed and grape seed polyphenols). Levels of lipids including TAGs and PLs in rats were investigated by shotgun-electrospray ionization tandem mass spectrometry (shotgun-ESI-MS). Results showed that high fat diet would give rise to the total TAGs and decreased total phosphatidylcholine (PC), phosphatidylethanolamine (PE) and phosphatidylserine (PS) (p < 0.05) in group C, S, R and F, compared with group Z. Results also showed that supplementary with rapeseed polyphenols or grape seed polyphenols reduced total TAGs and increased total PC, PE and PS (p < 0.05) in group S, R and F, compared with group C. Grape seed polyphenols and rapeseed polyphenols had certain regulatory effect on metabolism diseases such as fatty liver.
