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肺泡表面活性物质联用持续正压通气治疗新生儿呼吸窘迫综合征的临床观察

Clinical observation of pulmonary surfactant combined with continuous positive airway pressure in the treatment of neonatal respiratory distress syndrome
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摘要 目的:观察、研究肺泡表面活性物质联用持续正压通气(CPAP)治疗新生儿呼吸窘迫综合征的临床效果。方法:收治新生儿呼吸窘迫综合征患儿34例,随机分成两组,对照组采用肺泡表面活性物质治疗,观察组采用肺泡表面活性物质联用CPAP治疗,观察、对比两组患儿的动脉血氧分压(PaO_2),动脉血二氧化碳分压(PaCO_2)及氧合指数(PaO_2/FiO_2)和p H酸碱度,统计、对比两组患儿的不良并发症。结果:治疗后观察组PaO_2、PaCO_2、PaO_2/FiO_2及p H酸碱度明显比对照组好,不良并发症明显比对照组少(P<0.05)。结论:肺泡表面活性物质联用CPAP治疗新生儿呼吸窘迫综合征的临床效果好,不良并发症也减少。 Objective:To study the clinical effect of pulmonary surfactant combined with continuous positive airway pressure(CPAP)in the treatment of neonatal respiratory distress syndrome.Methods:34 patients with neonatal respiratory distress syndrome were selected.They were randomly divided into the two groups.Patients in the control group used pulmonary surfactant treatment.Patients in the observation were treated with group pulmonary surfactant combined with CPAP.The arterial oxygen partial pressure (PaO2),arterial carbon dioxide partial pressure(PaCO2)and oxygenation index (PaO2/FiO2)and PH value were observed and compared between groups,and adverse complications were compared.Results:After treatment,PaO2,PaCO2,PaO2/FiO2 and pH value of the observation group were significantly better than those in the control group,and the adverse complications were significantly less than those in the control group(P<0.05).Conclusion:The clinical effect of pulmonary surfactant combined with CPAP in the treatment of neonatal respiratory distress syndrome is significant,and the complications are reduced.
作者 季海莺 Ji Haiying(The People's Hospital of Lijiang Cith,Yunnan Province 674100)
出处 《中国社区医师》 2016年第4期64-65,共2页 Chinese Community Doctors
关键词 肺泡表面活性物质 持续正压通气 呼吸窘迫综合征 Pulmonary surfactant Continuous positive airway pressure Respiratory distress syndrome
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