摘要
目的 探讨急性热应激复合创伤后血浆一氧化氮 (NO)早期变化及其对血压的可能影响。方法 建立兔急性热应激复合创伤模型 ,按不同时间取血测定NO含量 ,全程监测血压变化。结果 急性热应激创伤后 1h左右兔血浆NO浓度下降 ,尔后升高 ,在高温和创伤条件下平均动脉压 (MAP)亦于 1h左右降至最低点 ,继之有一个短暂的回升 ,尔后迅速下降。结论 急性热应激复合创伤兔早期血浆NO浓度是先降低后升高 ,且与MAP的变化有一定关系。
Objective To study the possible effects of acute heat stress with trauma on early changes in plasma nitric oxide and blood pressure.Methods Rabbit model of acute heat stress with trauma was established.Blood specimens were collected from the rabbits at varied times and their levels of nitric oxide and mean arterial pressure(MAP)were measured.Results Plasma levels of nitric oxide declined about one hour after acute heat stress with trauma in rabbits and then increased,and their MAP declined to the lowest with hyperthermia and trauma for about one hour,then increased for a short time and rapidly declined again.Conclusion Acute heat stress with trauma in rabbits could cause their levels of nitric oxide declined first and then increased,which correlated with their MAP to a certain extent.
出处
《中国工业医学杂志》
CAS
北大核心
2002年第5期257-259,共3页
Chinese Journal of Industrial Medicine
基金
军队"十五"指令性课题资助 (课题编号 :0 1L0 51 )
关键词
急性热应激
创伤
一氧化氮
平均动脉压
Acute heat stress
Trauma
Nitric oxide
Mean arterial pressure
