摘要
目的 探讨Alzheimer's和Binswanger's病的临床鉴别点。方法 对40例Binswanger's病人和20例AD病人的临床症状和CT资料进行对照分析。结果 Binswanger's病组多有卒中、高血压、头昏或晕厥史,自知力多保留,CT特点为脑室周围白质低密度区(WMLA)和多发腔隙性梗塞(LI);AD组多无上述病史,多有情感改变和精神障碍及失语和失认,多无自知力,无局灶性神经系统体征,CT主要表现为皮层萎缩,侧脑室容积大。结论 鉴别是Binswanger's病还是AD应注意两点:一是神经系体征与精神障碍是否同时发生;二是检查是否有多发性脑梗塞和WMLA。
Objective To investigate the clinical difference between Alzheimer's disease (AD) and Binswanger's disease . Methods Control analysis was conducted for the clinical symptoms and CT data between AD and BD. Results Most cases in the group of Binswanger' s disaese had insight (P < 0.01) and the medical history of apoplexy, hypertension, dizziness, and faint( P < 0.01) . But memory and intelligence were damaged (100% ) . The characteristics of CT were low density area in periventricular white matter (WMLA) and multipul locular cerebral infarction (LI) . While the group of AD, in which the medical history above couldn't be found, had emotion change and mental disorders, aphonia and agnose, without insight and local nerve-systerm signs. Its principal CT expression was cortex atrophy (P < 0.01). By the comparation of the index of somatic part of lateral ventricle, we found that lateral ventricle capicity of AD patients was bigger. Conclusion Attention should be paid to the following two point in distinguishing AD and Binswanger's disease:1, whether nervous signs and wental disorders occur simultaneously, 2. whether multiple cerebtral infarction and WMLA were found in CT exemination.
出处
《山东精神医学》
2002年第3期144-146,共3页
Shangdong Archives of Psychiatry
