摘要
目的 比较帕罗西汀与氯丙咪嗪在 Alzheimer' s病抑郁症状治疗中的疗效和副反应。方法 帕罗西汀组 5 1例 ,氯丙咪嗪组 48例 ,均诊断为 AD,汉密尔顿抑郁量表 ( HAMD,1 7项 )≥ 1 8分。比较两组病人治疗后的 HAMD减分率 ,采用副反应量表 ( TESS)评定副反应。结果 帕罗西汀组与氯丙咪嗪组总体疗效相当 ,但帕罗西汀组起效较快 ,副反应发生率低。结论 帕罗西汀在
Objective To compare the effect and side effect of paroxetine and clomipramine.Methods 51 patients with Alzheimer's disease were divided into treating group paraxetine group and 48 patients with same symptom (controlled group with clomipramine).Clinical progress was examined with HAMD-17 and TESS.Results The overall effective rate of paroxetine group and clomipramine group were 98.04% and 95.5% respectively.There were not significant differences between two groups(P>0.05).But the side effects and the effect time of paroxetine group was lower remarkably than that of clomipramine group during the 2nd and 8th week of treatment(P<0.05).Conclusion In the treatment of Alzheimer's disease,Paroxetine has higher effective rate.
出处
《健康心理学杂志》
2004年第1期33-34,共2页
Health Psychology Journal
